{"id":"W4392848739","doi":"10.1503/jpn.230112","title":"Advances in the understanding of the pathophysiology of schizophrenia and bipolar disorder through induced pluripotent stem cell models","year":2024,"lang":"en","type":"review","venue":"Journal of Psychiatry and Neuroscience","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Schizophrenia (object-oriented programming); Induced pluripotent stem cell; Bipolar disorder; Neuroscience; Disease; Psychology; Psychiatry; Medicine; Biology; Cognition; Embryonic stem cell; Pathology; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006390044,0.0005952388,0.0006988831,0.001417735,0.0001755602,0.0006246718,0.0005885075,0.0007249428,0.002454514],"category_scores_gemma":[0.0005607188,0.0001700218,0.0004590547,0.001006688,0.0003133543,0.0007846813,0.0004626386,0.001543893,0.0009514486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004311958,"about_ca_system_score_gemma":0.000895672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007700708,"about_ca_topic_score_gemma":0.001301768,"domain_scores_codex":[0.9998668,0.00002658667,0.00002256433,0.00002327338,0.00005013401,0.00001060597],"domain_scores_gemma":[0.9997378,0.0001531793,0.00002523219,0.000009507715,0.0000562955,0.00001801592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007004072,0.00005180145,0.0001877018,0.02175439,0.0001053567,0.0003244967,0.00007630655,0.0005194187,0.006603832,0.01049143,0.01347909,0.9463362],"study_design_scores_gemma":[0.00002242652,0.0001289484,0.000955184,0.004627678,0.0002456478,0.001429614,0.00006594771,0.0001800409,0.002433145,0.005976796,0.9839094,0.00002519464],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001986123,0.9974415,0.0004351122,0.0003973322,0.0001887727,0.000006648191,0.00003164086,0.00001061116,0.001289716],"genre_scores_gemma":[0.0008178837,0.9982744,0.0003804925,0.0001519715,0.0000870981,0.000006300899,0.00003027788,0.000001218762,0.0002503116],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002454514,"threshold_uncertainty_score":0.008211195,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05271654115586199,"score_gpt":0.3208007044084232,"score_spread":0.2680841632525612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}