{"id":"W4392862580","doi":"10.1093/molbev/msae055","title":"Fermentation Practices Select for Thermostable Endolysins in Phages","year":2024,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université Laval","funders":"Argonne National Laboratory; Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Eli Lilly and Company; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; U.S. Department of Energy; Office of Science; National Science Foundation","keywords":"Lysin; Biology; Streptococcus thermophilus; Lytic cycle; Bacteriophage; Niche; Bacteria; Genetics; Microbiology; Biochemistry; Escherichia coli; Gene; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001059058,0.00005240886,0.00004778246,0.0000310967,0.0000578461,0.000023714,0.00002733494,0.00005156975,0.0001369043],"category_scores_gemma":[0.00002484873,0.0000465733,0.00002097932,0.00009382364,0.00004319464,0.0001602282,0.00002128259,0.00005610571,0.0000331392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007494423,"about_ca_system_score_gemma":0.000006486904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004112849,"about_ca_topic_score_gemma":0.0002065112,"domain_scores_codex":[0.9995841,0.00004183244,0.00007263461,0.0001729361,0.00001554726,0.0001129848],"domain_scores_gemma":[0.9998858,0.00002586284,0.00003125141,0.00004026051,0.000002812088,0.00001403937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00001621124,0.00001852147,0.002037997,0.000007159477,0.000008764548,0.000002018882,0.00009378284,0.00002515356,0.9917541,0.0009006228,0.0001607488,0.004974955],"study_design_scores_gemma":[0.001084885,0.0007125623,0.5699836,0.00008912661,0.0001457293,0.0001580677,0.0003729955,0.01382816,0.3309692,0.01980572,0.06229314,0.0005568106],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.975297,0.0006681299,0.02239148,0.0004936749,0.0001442896,0.0001697878,0.00001026464,0.0000222679,0.0008030987],"genre_scores_gemma":[0.9987437,0.00005245216,0.0006965648,0.00008288705,0.00001615065,0.00003494986,0.0000344724,0.000004759856,0.0003340458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6607849,"threshold_uncertainty_score":0.1899204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009106944425465866,"score_gpt":0.320122610628519,"score_spread":0.3110156662030532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}