{"id":"W4392862580","doi":"10.1093/molbev/msae055","title":"Fermentation Practices Select for Thermostable Endolysins in Phages","year":2024,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université Laval","funders":"Argonne National Laboratory; Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Eli Lilly and Company; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; U.S. Department of Energy; Office of Science; National Science Foundation","keywords":"Lysin; Biology; Streptococcus thermophilus; Lytic cycle; Bacteriophage; Niche; Bacteria; Genetics; Microbiology; Biochemistry; Escherichia coli; Gene; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005149527,0.000319547,0.0004596394,0.0003542119,0.0003280693,0.001174696,0.0002393279,0.0003638751,0.0008730033],"category_scores_gemma":[0.0007660613,0.000174447,0.0003464853,0.0004396545,0.0002390268,0.0004082157,0.0009207539,0.0005467127,0.0003189013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002706435,"about_ca_system_score_gemma":0.0003494283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007005131,"about_ca_topic_score_gemma":0.001114487,"domain_scores_codex":[0.9993617,0.0001152633,0.00006039841,0.0001540957,0.000136323,0.0001722125],"domain_scores_gemma":[0.9994283,0.0001554756,0.0001305388,0.00007047578,0.0001205766,0.00009451302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001140274,0.00007841713,0.006830154,0.00003867001,0.00001533651,0.00009204378,0.0001231367,0.00005571728,0.9890146,0.00006109736,0.00003232569,0.003544549],"study_design_scores_gemma":[0.00001875245,0.001273678,0.2682908,0.00006277837,0.0001025062,0.001500871,0.001586881,0.001996418,0.7204005,0.0002988261,0.004423424,0.000044537],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982709,0.0003152466,0.0006725808,0.00004005136,0.000008230676,0.00001479956,0.00006901925,0.00001259123,0.0005965496],"genre_scores_gemma":[0.9969054,0.0001955322,0.001802805,0.00005779171,0.000007932788,0.00001581053,0.0002200437,0.00001832448,0.0007762728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001174696,"threshold_uncertainty_score":0.002920449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009106944425465866,"score_gpt":0.320122610628519,"score_spread":0.3110156662030532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}