{"id":"W4392881813","doi":"10.1101/2024.03.15.585219","title":"Impact of extracellular current flow on action potential propagation in myelinated axons","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Neuroscience and Neural Engineering","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Axon; Node of Ranvier; Resistive touchscreen; Biophysics; Neuroscience; Node (physics); Physics; Action potential; Extracellular; Sodium channel; Chemistry; Myelin; Electrophysiology; Computer science; Biology; Acoustics; Sodium; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001476701,0.0002999813,0.0002707668,0.0002260719,0.0004126789,0.0007978855,0.0003820913,0.0005478415,0.001560067],"category_scores_gemma":[0.001163087,0.0001769863,0.0002992946,0.000153071,0.0005874187,0.0007198684,0.0005555641,0.0004599375,0.0001134501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000609797,"about_ca_system_score_gemma":0.0005197726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002933702,"about_ca_topic_score_gemma":0.001356877,"domain_scores_codex":[0.9999179,0.00001887377,0.000004880769,0.00001127516,0.00002136728,0.00002572729],"domain_scores_gemma":[0.9995709,0.0002480832,0.00006998642,0.00002131603,0.00003984608,0.00004992697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0001825827,0.00008918675,0.003073633,0.00009436885,0.0000341038,0.0004545588,0.00008495752,0.9501101,0.03853663,0.004783286,0.0001804327,0.002376091],"study_design_scores_gemma":[0.00003389623,0.0001866152,0.001451589,0.00002149295,0.00001871366,0.00007256411,0.00006138582,0.9867018,0.0093893,0.0017174,0.0003246669,0.00002056844],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874423,0.0001853228,0.009246815,0.0001155648,0.00002356939,0.00001064041,0.0000753912,0.00004603626,0.002854255],"genre_scores_gemma":[0.9986512,0.00008056284,0.0008170462,0.00001134866,0.000002721266,0.000006615675,0.00002220923,0.0000077774,0.0004004363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002933702,"threshold_uncertainty_score":0.005833268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03387058596501633,"score_gpt":0.2793425468268976,"score_spread":0.2454719608618812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}