{"id":"W4392883980","doi":"10.1016/j.mucimm.2024.03.002","title":"PD-1 regulates ILC3-driven intestinal immunity and homeostasis","year":2024,"lang":"en","type":"article","venue":"Mucosal Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Calgary","funders":"Cancer Council NSW; National Health and Medical Research Council; Medical Research Council; Fraser Institute; Canadian Institutes of Health Research; University of Queensland; Cancer Australia; Canadian Cancer Society; State Government of Victoria; Australian Government; Multiple Sclerosis Australia; Melanoma Research Alliance; Alberta Cancer Foundation; Cure Cancer Australia Foundation; Arnie Charbonneau Cancer Institute, University of Calgary","keywords":"Context (archaeology); Inflammation; Biology; Immunology; Immune system; Intestinal mucosa; Homeostasis; Immunity; Innate lymphoid cell; Cell biology; Cancer research; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002958036,0.000378114,0.0004961809,0.0003317208,0.0004001403,0.00007211477,0.0003897209,0.0005437302,0.0005702765],"category_scores_gemma":[0.0002609055,0.0003371836,0.0001272328,0.0003586287,0.001049164,0.0002206599,0.0004260785,0.0009807574,0.001976105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007730776,"about_ca_system_score_gemma":0.0001721981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004040957,"about_ca_topic_score_gemma":0.00007691173,"domain_scores_codex":[0.9978458,0.0003768741,0.0004274906,0.0005719719,0.00004043322,0.0007374866],"domain_scores_gemma":[0.9988344,0.0004268148,0.00007972631,0.0005082379,0.0001134611,0.00003730083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003337411,0.0001780655,0.001344256,0.0001512388,0.0009326943,0.0001481318,0.002354711,0.000001510063,0.9102266,0.01450964,0.008213849,0.06160558],"study_design_scores_gemma":[0.002205934,0.001601564,0.04134389,0.000329794,0.0002816396,0.004201412,0.001589641,0.00007190046,0.2365563,0.004740368,0.7059832,0.001094323],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9499336,0.04174794,0.0001738752,0.0005931297,0.002575307,0.0002319796,0.000595228,0.0005872058,0.003561734],"genre_scores_gemma":[0.9943932,0.001809094,0.000258929,0.0001503202,0.00008519561,0.00003624936,0.0003558747,0.00005041711,0.002860757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6977693,"threshold_uncertainty_score":0.999908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01470050530742925,"score_gpt":0.235882599034294,"score_spread":0.2211820937268648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}