{"id":"W4392884522","doi":"10.1007/s00428-024-03775-y","title":"Molecularly defined sinonasal malignancies: an overview with focus on the current WHO classification and recently described provisional entities","year":2024,"lang":"en","type":"article","venue":"Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Univerzita Karlova v Praze","keywords":"Head and neck; Pathology; Histopathology; Immunohistochemistry; Medicine; Molecular pathology; Medical diagnosis; IDH1; Biology; Gene; Mutation; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007343444,0.0004482867,0.0003788552,0.00009969974,0.0002682698,0.0001361228,0.0004560335,0.0001813248,0.00001787386],"category_scores_gemma":[0.000309914,0.0002622718,0.0001460997,0.0002246605,0.0007908609,0.00002629841,0.0002043834,0.0005943092,0.00001607147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003044685,"about_ca_system_score_gemma":0.0004231152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003697157,"about_ca_topic_score_gemma":0.00003267701,"domain_scores_codex":[0.9971806,0.000485093,0.0004399652,0.001006751,0.0003937987,0.0004937426],"domain_scores_gemma":[0.9985508,0.0002597591,0.0001493416,0.0007682191,0.0001109627,0.0001609533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001242272,0.0005879563,0.0009280402,0.0005785754,0.0006402555,0.0001078933,0.001294095,0.0003063861,0.5956167,0.08391432,0.005730984,0.3090525],"study_design_scores_gemma":[0.01083611,0.0293901,0.08643122,0.009890185,0.00282282,0.0003321173,0.006561938,0.08450565,0.2749614,0.1911219,0.2957289,0.007417616],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9381487,0.0514705,0.005482513,0.002164875,0.0003611984,0.0006551783,0.0001156199,0.000128658,0.001472699],"genre_scores_gemma":[0.984521,0.01193568,0.00154998,0.0009131839,0.0003445996,0.0001299164,0.0004102909,0.00005521999,0.0001401156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3206553,"threshold_uncertainty_score":0.999983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0598374005687743,"score_gpt":0.3630593031935129,"score_spread":0.3032219026247386,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}