{"id":"W4392906520","doi":"10.32920/25417297.v1","title":"The Synthesis of Molecular Probes Based on Cystic Fibrosis Drugs for Biological Research","year":2024,"lang":"en","type":"preprint","venue":"","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University","funders":"Sickkids Research Institute; Hospital for Sick Children","keywords":"Cystic fibrosis; Computational biology; Nanotechnology; Computer science; Pharmacology; Medicine; Biology; Internal medicine; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004689119,0.0006727502,0.0003320812,0.0004073756,0.0002962781,0.0004002469,0.0004549582,0.001076919,0.005408023],"category_scores_gemma":[0.0005483779,0.0004260238,0.0004286313,0.0003411186,0.0004345611,0.0007288234,0.0004517245,0.0016397,0.002944516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006079635,"about_ca_system_score_gemma":0.0004382114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000238085,"about_ca_topic_score_gemma":0.0004069267,"domain_scores_codex":[0.9997204,0.00006443079,0.0000157483,0.00007226071,0.00007012056,0.00005704171],"domain_scores_gemma":[0.9998226,0.00005390675,0.00004000199,0.00002565746,0.00002851815,0.00002943023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008877313,0.00007862629,0.00006445824,0.0006644201,0.0000275047,0.0002125397,0.000108991,0.0006199391,0.9339153,0.02488158,0.002717948,0.03662004],"study_design_scores_gemma":[0.00004350332,0.000446552,0.0001803154,0.0000597057,0.00002198261,0.000208587,0.00002197712,0.000753741,0.8992908,0.002012777,0.09693637,0.0000236945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.23162,0.06412206,0.569695,0.006170686,0.005207343,0.002443537,0.002890454,0.002303306,0.1155477],"genre_scores_gemma":[0.5759509,0.03482264,0.3237723,0.003670132,0.0003669749,0.002891277,0.001967913,0.0003288253,0.0562289],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.005408023,"threshold_uncertainty_score":0.01809162,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08442294997552995,"score_gpt":0.4039146617458465,"score_spread":0.3194917117703165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}