{"id":"W4392907173","doi":"10.1016/j.mucimm.2024.03.003","title":"Dendritic cell-mediated responses to secreted Cryptosporidium effectors promote parasite-specific CD8+ T cell responses","year":2024,"lang":"en","type":"article","venue":"Mucosal Immunology","topic":"Parasitic Infections and Diagnostics","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; European Molecular Biology Organization; Louisiana Academy of Sciences; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Commonwealth of Pennsylvania","keywords":"Effector; Cryptosporidium; Cell mediated immunity; Parasite hosting; Biology; Dendritic cell; Cell; Immunology; Immunity; CD8; Cell biology; T cell; Microbiology; Immune system; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009725043,0.0002928447,0.0001791214,0.0001325481,0.000105079,0.0002356069,0.00007175139,0.0001999795,0.001682963],"category_scores_gemma":[0.0001092352,0.00009795199,0.0001237399,0.00006582973,0.0001557553,0.0001137811,0.0002101857,0.0006744231,0.0004852166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001604066,"about_ca_system_score_gemma":0.0001441394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009147123,"about_ca_topic_score_gemma":0.0002257338,"domain_scores_codex":[0.9998871,0.00002091273,0.000006614212,0.00002261943,0.0000212249,0.00004158695],"domain_scores_gemma":[0.9999315,0.00001226409,0.00001080546,0.000005713932,0.000009590962,0.00003020667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001611859,0.00005353475,0.000267708,0.00004553525,0.000002340392,0.00007564932,0.00001821493,0.00005011625,0.9966875,0.00004435931,0.00008288636,0.002510943],"study_design_scores_gemma":[0.0002807669,0.001837141,0.01048481,0.00002706326,0.00003293964,0.0007007312,0.00009562403,0.002129298,0.976843,0.0001983495,0.007363208,0.000007093766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948308,0.0007490999,0.001524651,0.0001535744,0.00005860825,0.00007085981,0.0001263912,0.0001139114,0.002372065],"genre_scores_gemma":[0.9960119,0.0004144401,0.001376779,0.000067765,0.00003108087,0.00002842702,0.0001131808,0.0000136957,0.001942709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001682963,"threshold_uncertainty_score":0.005630076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01179368951882423,"score_gpt":0.2590922805243775,"score_spread":0.2472985910055533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}