{"id":"W4392923906","doi":"10.1007/s12325-024-02822-z","title":"Matching-Adjusted Indirect Comparison of Brexucabtagene Autoleucel (ZUMA-2) and Pirtobrutinib (BRUIN) in Patients with Relapsed/Refractory Mantle Cell Lymphoma Previously Treated with a Covalent Bruton Tyrosine Kinase Inhibitor","year":2024,"lang":"en","type":"article","venue":"Advances in Therapy","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"MD Precision (Canada); Precision Nanosystems (Canada)","funders":"National Cancer Institute; Kite Pharma","keywords":"Mantle cell lymphoma; Medicine; Internal medicine; Hazard ratio; Population; Oncology; Progression-free survival; Confidence interval; Gastroenterology; Lymphoma; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01035929,0.001012304,0.001444462,0.0006336606,0.0002025533,0.0009272905,0.001305653,0.0009878851,0.005588852],"category_scores_gemma":[0.01803139,0.0004769596,0.006247825,0.000558021,0.0006063108,0.0007752403,0.001490813,0.001394099,0.0003753146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009467197,"about_ca_system_score_gemma":0.0006894131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001125382,"about_ca_topic_score_gemma":0.001049576,"domain_scores_codex":[0.9901457,0.007561564,0.0004646885,0.0008776601,0.0004782735,0.0004720136],"domain_scores_gemma":[0.9918638,0.00483917,0.001841054,0.0008971058,0.0002312301,0.000327466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6499955,0.00260007,0.1671612,0.002736212,0.0792764,0.0003437485,0.0004466788,0.02336274,0.002847036,0.00352655,0.001708368,0.0659954],"study_design_scores_gemma":[0.1099824,0.2348458,0.3785554,0.0009132127,0.1337361,0.001281569,0.0008499006,0.1071877,0.008762679,0.01381213,0.009766587,0.0003066188],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915736,0.001769672,0.003557744,0.000129707,0.0001295232,0.0004611482,0.001109067,0.00003013097,0.001239265],"genre_scores_gemma":[0.9969771,0.0002024075,0.001300164,0.00007872609,0.00002447656,0.000369,0.0005830572,0.000007033052,0.0004581914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01035929,"threshold_uncertainty_score":0.05478591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01086648479791213,"score_gpt":0.2654537285972432,"score_spread":0.2545872437993311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}