{"id":"W4392931790","doi":"10.1016/j.jtho.2024.03.015","title":"The International Association for the Study of Lung Cancer (IASLC) Staging Project for Lung Cancer: Recommendation to Introduce Spread Through Air Spaces as a Histologic Descriptor in the Ninth Edition of the TNM Classification of Lung Cancer. Analysis of 4061 Pathologic Stage I NSCLC","year":2024,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Lung Cancer Diagnosis and Treatment","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"Sun Yat-sen University Cancer Center; University of Sydney; University of Colorado Colorado Springs; National Cancer Institute; Arthrex GmbH; Instituto Nacional do Câncer, Ministério da Saúde; Shanghai Chest Hospital; Peking University; All-India Institute of Medical Sciences; Technische Universität München; Shanghai Jiao Tong University; University of Queensland; Instituto Nacional de Cancerología; Chartered Institute of Management Accountants; Seoul National University Bundang Hospital; Columbus State University; Université Laval; Massachusetts General Hospital; Institut National Du Cancer; Memorial Sloan-Kettering Cancer Center; International Association for the Study of Lung Cancer; Guangdong Provincial People's Hospital; Icahn School of Medicine at Mount Sinai; B.P. Koirala Institute of Health Sciences; Boehringer Ingelheim","keywords":"Medicine; Lung cancer; Lymphovascular invasion; Adenocarcinoma; Stage (stratigraphy); Univariate analysis; Cancer; Oncology; Internal medicine; Radiology; Pathology; Multivariate analysis; Metastasis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008142817,0.0003826346,0.0008228743,0.003649475,0.000547407,0.001068603,0.001292547,0.000556481,0.002679307],"category_scores_gemma":[0.007867794,0.0001924112,0.001004915,0.004533449,0.0004041606,0.0005257106,0.001066099,0.001506301,0.001090421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00105334,"about_ca_system_score_gemma":0.004425045,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0239076,"about_ca_topic_score_gemma":0.0555451,"domain_scores_codex":[0.9977793,0.0007773351,0.0004530553,0.0001362575,0.000663715,0.0001903771],"domain_scores_gemma":[0.9919904,0.0009803846,0.00166153,0.0005158167,0.004088909,0.0007630529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007025905,0.0001478266,0.8232354,0.0005614237,0.0003212592,0.0001137039,0.0001524152,0.0004380773,0.001189499,0.0009964211,0.1053531,0.06678836],"study_design_scores_gemma":[0.0002019594,0.0002140548,0.937635,0.0003104595,0.0003535628,0.0003201102,0.0003844572,0.001279881,0.0006554989,0.0007414875,0.05786838,0.00003515068],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5301126,0.03384416,0.0493701,0.02420554,0.008169054,0.005661537,0.2773807,0.0008735661,0.07038274],"genre_scores_gemma":[0.700364,0.01158057,0.06727076,0.00405527,0.001394235,0.004657219,0.193636,0.0003679699,0.01667408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0239076,"threshold_uncertainty_score":0.04753691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0533073388116943,"score_gpt":0.4766270188299929,"score_spread":0.4233196800182986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}