{"id":"W4392984411","doi":"10.1091/mbc.e23-10-0386","title":"SARS-CoV-2 Orf6 is positioned in the nuclear pore complex by Rae1 to inhibit nucleocytoplasmic transport","year":2024,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Cancer Institute; Canadian Institutes of Health Research; National Institute of General Medical Sciences; National Natural Science Foundation of China","keywords":"Biology; Nuclear pore; Nuclear transport; Cell biology; RNA; Inner membrane; Nuclear export signal; Interferon; Cell nucleus; Nucleus; Virology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001770319,0.0002323871,0.0002681602,0.0001206973,0.0001762193,0.0003493317,0.0002531127,0.0003150603,0.001092898],"category_scores_gemma":[0.0001915715,0.0001621463,0.0002353247,0.00006698625,0.0002536899,0.0002236521,0.0002138309,0.0004019729,0.0006051349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002796479,"about_ca_system_score_gemma":0.0001726028,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002505584,"about_ca_topic_score_gemma":0.0003270279,"domain_scores_codex":[0.9998515,0.00003801484,0.00001368473,0.00002802635,0.00003504644,0.00003370692],"domain_scores_gemma":[0.9998792,0.00003069861,0.00003709353,0.00001819911,0.00001231177,0.00002245286],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006740379,0.00001461171,0.00008628865,0.00001242811,0.000002513802,0.00003002087,0.000005863466,0.00009323304,0.999175,0.0001014322,0.00001874106,0.0003924453],"study_design_scores_gemma":[0.00001521051,0.0001270362,0.00161994,0.000003552904,0.000005412574,0.0002371731,0.0000159204,0.001689612,0.9946333,0.00005149003,0.001597949,0.000003305168],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99533,0.001359804,0.001836216,0.0001007051,0.00001742907,0.000008238352,0.00008339769,0.00005539453,0.00120898],"genre_scores_gemma":[0.9966664,0.000283479,0.001370322,0.00003259456,0.000004986054,0.00000946464,0.0001869043,0.00001462819,0.001431157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001092898,"threshold_uncertainty_score":0.003656149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007335699898313367,"score_gpt":0.2441113989332654,"score_spread":0.236775699034952,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}