{"id":"W4393011646","doi":"10.1111/acel.14149","title":"Effect of long‐term caloric restriction on telomere length in healthy adults: CALERIE™ 2 trial analysis","year":2024,"lang":"en","type":"article","venue":"Aging Cell","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Environmental Health Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Institute on Aging","keywords":"Attrition; Caloric theory; Telomere; Biology; Physiology; Internal medicine; Medicine; Endocrinology; Genetics; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003090986,0.00123327,0.002804455,0.0002968957,0.0003731199,0.0009896174,0.0005259494,0.00123014,0.003891738],"category_scores_gemma":[0.002983581,0.0004168039,0.00339128,0.0003925528,0.0005400795,0.0009078009,0.0004977078,0.001900074,0.0002566024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004672451,"about_ca_system_score_gemma":0.0006782797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001018504,"about_ca_topic_score_gemma":0.002002717,"domain_scores_codex":[0.9986007,0.0007722443,0.0001342498,0.0002600424,0.00008765018,0.0001452132],"domain_scores_gemma":[0.9988385,0.0004213769,0.0002947981,0.000136575,0.0001136814,0.0001949935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9611053,0.0012509,0.005855022,0.00217427,0.01453607,0.00005517752,0.00005512277,0.0003211634,0.001833835,0.0001364542,0.0008280445,0.01184869],"study_design_scores_gemma":[0.7643819,0.1228592,0.05326383,0.0009876663,0.05086716,0.0001416502,0.0001235344,0.002129566,0.001679343,0.0008363379,0.002635812,0.0000939442],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9756601,0.01875125,0.0009112534,0.0006680126,0.0004929514,0.00111729,0.001001502,0.00006117354,0.001336395],"genre_scores_gemma":[0.9926499,0.002307787,0.0008155364,0.0005356239,0.0002904033,0.001555515,0.0005057644,0.00001467569,0.00132489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003891738,"threshold_uncertainty_score":0.01634693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009280630103348191,"score_gpt":0.3024815221237215,"score_spread":0.2932008920203733,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}