{"id":"W4393043003","doi":"10.14740/wjon1751","title":"High Ki67 Gene Expression Is Associated With Aggressive Phenotype in Hepatocellular Carcinoma","year":2024,"lang":"en","type":"article","venue":"World Journal of Oncology","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; National Cancer Institute; National Institutes of Health; Roswell Park Cancer Institute; U.S. Department of Defense","keywords":"Medicine; Hepatocellular carcinoma; Gene signature; Immunohistochemistry; Phenotype; Cancer research; Oncology; Proliferation Marker; Cell cycle; Gene expression; Pathology; Internal medicine; Cancer; Gene; Biology; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004575703,0.0002260267,0.0007423519,0.0006809629,0.00004751841,0.00002600528,0.00011757,0.0001712123,0.0005853688],"category_scores_gemma":[0.00008134099,0.0001539491,0.0001929243,0.0006800774,0.00008186257,0.000123095,0.00003693409,0.000620639,0.00003314707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006181816,"about_ca_system_score_gemma":0.0006734869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005050976,"about_ca_topic_score_gemma":0.00005788006,"domain_scores_codex":[0.9982614,0.0001992731,0.0005847818,0.000249864,0.0003678395,0.0003368247],"domain_scores_gemma":[0.9987341,0.0002482656,0.0004187775,0.0001696835,0.0002149608,0.0002142585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008278558,0.0005110753,0.9065256,0.00005980132,0.0003624389,0.05994256,0.001003675,0.00000354101,0.01606005,0.00006556899,0.004431199,0.01020665],"study_design_scores_gemma":[0.03276585,0.02105254,0.4147945,0.009414258,0.004116591,0.008886269,0.0005145646,0.005948928,0.4032008,0.001661854,0.09629082,0.001353028],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843709,0.01086133,0.0000647624,0.002810884,0.0004730624,0.0002878774,0.000008629143,0.00002602066,0.001096566],"genre_scores_gemma":[0.9960591,0.000220379,0.001702733,0.0003876125,0.0003555609,0.00001448949,0.00002441031,0.00004247348,0.0011932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4917311,"threshold_uncertainty_score":0.6409377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0396010341883181,"score_gpt":0.2733569033091027,"score_spread":0.2337558691207846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}