{"id":"W4393043011","doi":"10.14740/wjon1790","title":"Predictors of Immunotherapy Efficacy in Metastatic Non-Small Cell Lung Cancer: Lung Immune Prognostic Index and Immune-Related Toxicity","year":2024,"lang":"en","type":"article","venue":"World Journal of Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Internal medicine; Lung cancer; Common Terminology Criteria for Adverse Events; Gastroenterology; Immune system; Adverse effect; Response Evaluation Criteria in Solid Tumors; Absolute neutrophil count; Toxicity; Progressive disease; Disease; Immunology; Neutropenia","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009333502,0.0001624137,0.0003108027,0.0003972886,0.0001913422,0.0003643297,0.000176363,0.0002322745,0.001158939],"category_scores_gemma":[0.002111319,0.00007993281,0.0003829832,0.0006042821,0.0001661804,0.0002800144,0.0002447629,0.0003958157,0.0001542339],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002331241,"about_ca_system_score_gemma":0.000264349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003502966,"about_ca_topic_score_gemma":0.0006084446,"domain_scores_codex":[0.9996427,0.00009451454,0.0000613771,0.00006351528,0.00008450111,0.00005341686],"domain_scores_gemma":[0.9979624,0.0004712934,0.001110043,0.00005689244,0.000149253,0.0002501513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000153117,0.00001355923,0.9988991,0.000008305115,0.00001796607,0.00002043813,0.000005134313,0.00003182774,0.00008761996,0.000003773686,0.00002191914,0.000737226],"study_design_scores_gemma":[0.00001140865,0.0002482264,0.998859,0.000005021594,0.00003213208,0.000304449,0.00002739884,0.0002746251,0.00008828561,0.00001886134,0.0001289118,0.00000165516],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989631,0.0004879701,0.00007681816,0.00002805838,0.000003768533,0.000008968435,0.0001890771,0.000001583796,0.0002405484],"genre_scores_gemma":[0.9996735,0.00005187716,0.00003624892,0.000008747119,0.000006792451,0.000005334105,0.000185272,4.485455e-7,0.00003176941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001158939,"threshold_uncertainty_score":0.004936099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0104257587955836,"score_gpt":0.2996332837192387,"score_spread":0.2892075249236551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}