{"id":"W4393044211","doi":"10.1002/smll.202309495","title":"Pulsed Photothermal Therapy of Solid Tumors as a Precondition for Immunotherapy","year":2024,"lang":"en","type":"article","venue":"Small","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Doug Bragg Enterprises (Canada); Prevention of Organ Failure; University of British Columbia","funders":"Canadian Institutes of Health Research; Mitacs","keywords":"Photothermal therapy; CD80; Immunotherapy; Cancer research; Immunogenic cell death; Immune system; Materials science; Hyperthermia; CD86; Cytotoxic T cell; Medicine; T cell; Immunology; Biology; Nanotechnology; CD40; In vitro; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001666927,0.0001972841,0.000184647,0.0001170796,0.0001666734,0.0003154775,0.000176485,0.000396037,0.001587807],"category_scores_gemma":[0.0001588681,0.0001268302,0.0001692077,0.0001082915,0.0003185913,0.0003621886,0.0003004135,0.0007970762,0.0004620861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002551443,"about_ca_system_score_gemma":0.0002086379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001259015,"about_ca_topic_score_gemma":0.0001891826,"domain_scores_codex":[0.9998801,0.00001989493,0.000005815959,0.00002898223,0.0000489375,0.00001616733],"domain_scores_gemma":[0.9999211,0.00002625781,0.00002054111,0.00001001648,0.00001182914,0.00001030214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002742279,0.00001439499,0.0000466966,0.0000947694,0.000002642,0.00003793823,0.00001595979,0.0001708335,0.9935445,0.001073574,0.0001413409,0.004830009],"study_design_scores_gemma":[0.000007746999,0.0002300649,0.000469225,0.00001736143,0.000007050548,0.0002519956,0.00001617776,0.001490853,0.9866589,0.0005487864,0.01029491,0.000006789907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7023107,0.04418746,0.2304698,0.00158974,0.000819427,0.0002723343,0.0003799779,0.0005532436,0.0194174],"genre_scores_gemma":[0.9546322,0.007873548,0.0302118,0.0005009108,0.0001034541,0.0001572677,0.0001653108,0.00006754497,0.006287933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001587807,"threshold_uncertainty_score":0.005311728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01414990936554221,"score_gpt":0.245748860127027,"score_spread":0.2315989507614847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}