{"id":"W4393072112","doi":"10.1158/1538-7445.am2024-6095","title":"Abstract 6095: Lung cancer risk assessment with the INTEGRAL protein panel: Preliminary results from development and validation in the Lung Cancer Cohort Consortium","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Health, Environment, Cognitive Aging","field":"Environmental Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Medicine; Lung cancer; Cancer; Cohort; Oncology; Internal medicine; Lung","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0369866,0.001220037,0.0005702089,0.0006357906,0.000583448,0.001084131,0.002023833,0.001049982,0.001150878],"category_scores_gemma":[0.02875116,0.0003427723,0.0009791002,0.0008817398,0.0009112001,0.0005963703,0.002471011,0.001331838,0.0006122846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008272471,"about_ca_system_score_gemma":0.001801143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01049248,"about_ca_topic_score_gemma":0.008211895,"domain_scores_codex":[0.9890553,0.007530954,0.0002795187,0.001213325,0.001607614,0.0003132399],"domain_scores_gemma":[0.9861823,0.005979239,0.0009379279,0.00329292,0.002611289,0.0009963016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01315838,0.003057678,0.878104,0.0002605863,0.002311604,0.0002717885,0.0006426097,0.03111194,0.01294668,0.0007168601,0.009851517,0.04756638],"study_design_scores_gemma":[0.003392037,0.008930142,0.8279549,0.0001159917,0.001339182,0.0006740504,0.0003269466,0.128781,0.01934081,0.001649493,0.007323747,0.0001716961],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9766614,0.0003531723,0.01522204,0.0003328423,0.0000308913,0.0005044634,0.005620549,0.0002940028,0.0009807892],"genre_scores_gemma":[0.9494036,0.0001460414,0.02595642,0.0002337336,0.00003693392,0.0005698724,0.02286923,0.0000963097,0.0006877482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0369866,"threshold_uncertainty_score":0.1956062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05645123146288197,"score_gpt":0.3935363698912951,"score_spread":0.3370851384284131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}