{"id":"W4393087794","doi":"10.1111/pbi.14342","title":"Bacterial growth‐mediated systems remodelling of <i>Nicotiana benthamiana</i> defines unique signatures of target protein production in molecular pharming","year":2024,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island; Agriculture and Agri-Food Canada; Bruker (Canada); Performance Plants (Canada); University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; University of Guelph; University of Ottawa","keywords":"Biology; Nicotiana benthamiana; Computational biology; Proteomics; Proteome; Biotechnology; Cell biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002745418,0.0001350902,0.0002078408,0.0002486703,0.00003485807,0.00001513327,0.0002071065,0.0003890059,0.00000365544],"category_scores_gemma":[0.00005672848,0.000118783,0.00006747007,0.0002294124,0.00009304035,0.000007990593,0.00002943424,0.0003637808,7.126296e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001419013,"about_ca_system_score_gemma":0.0001121649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003678576,"about_ca_topic_score_gemma":0.00001658732,"domain_scores_codex":[0.9989648,0.00005463067,0.0004244391,0.0002550866,0.0001055053,0.0001955126],"domain_scores_gemma":[0.9995949,0.00001017463,0.0001517647,0.0001509886,0.0000576268,0.00003450973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007028055,0.00005291614,0.00006956414,0.0001246193,0.00007830923,0.00002667443,0.00001862938,0.0007580491,0.9970433,0.001376049,0.000131371,0.0002502672],"study_design_scores_gemma":[0.0002126658,0.00009059808,0.00002000049,0.0002765909,0.00002210629,0.0003442408,0.00003611695,0.0008572749,0.9944572,0.0002701447,0.003295415,0.0001176449],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802428,0.007143699,0.01103604,0.000691993,0.0002889711,0.0002945178,0.0002476571,0.0000266161,0.00002763621],"genre_scores_gemma":[0.9964601,0.001544758,0.001686276,0.00000824367,0.0001015273,0.00001467273,0.0001545117,0.00001659513,0.00001330128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01621724,"threshold_uncertainty_score":0.4843829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007182424759580809,"score_gpt":0.2107962130632338,"score_spread":0.203613788303653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}