{"id":"W4393089268","doi":"10.1158/1538-7445.am2024-7335","title":"Abstract 7335: Characterizing germline variants in patients with small cell lung cancer","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; Toronto General Hospital; Western University","funders":"","keywords":"Germline; Cancer; Lung cancer; Medicine; Oncology; Internal medicine; Biology; Cancer research; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001023268,0.0002647006,0.0004432512,0.0006877594,0.0001639838,0.0001568716,0.0002816653,0.00011582,0.001440921],"category_scores_gemma":[0.000110325,0.0001959234,0.00006964002,0.001420261,0.0002282473,0.000246681,0.0002434938,0.001584266,0.00007574975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001938428,"about_ca_system_score_gemma":0.001890851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003404202,"about_ca_topic_score_gemma":0.001072611,"domain_scores_codex":[0.996078,0.0001016246,0.0003499778,0.0007912604,0.001432296,0.001246846],"domain_scores_gemma":[0.9983217,0.0002332413,0.00004033909,0.0004584064,0.0006216977,0.0003246563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002894772,0.00065315,0.8863896,0.009046762,0.000601883,0.001171776,0.002699508,0.00003747416,0.04100623,0.00005463956,0.02125154,0.03419271],"study_design_scores_gemma":[0.003085692,0.0003242668,0.9721655,0.004397488,0.00005253033,0.000001958644,0.00009967788,0.0001965079,0.004966355,0.00001379315,0.01441389,0.0002823328],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9786176,0.01305344,0.000007387663,0.00315032,0.0003495942,0.001660329,0.0001467923,0.00009774849,0.00291676],"genre_scores_gemma":[0.9912442,0.003075665,0.0000743887,0.0001740655,0.0006417898,0.00111878,0.00004113897,0.000104608,0.003525343],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08577595,"threshold_uncertainty_score":0.9994719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06340972096898669,"score_gpt":0.4157031245460039,"score_spread":0.3522934035770172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}