{"id":"W4393093306","doi":"10.1158/1538-7445.am2024-6962","title":"Abstract 6962: Shed Trop2 drives prostate cancer progression and Trop2 is a novel tissue prognostic biomarker and a candidate urinary marker for prostate cancer","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Prostate cancer; Medicine; Biomarker; Cancer; Prostate; Oncology; Urinary system; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001818211,0.0002178581,0.0002443963,0.0003688004,0.0002378282,0.000546484,0.0001511228,0.0002607159,0.002590992],"category_scores_gemma":[0.0002807172,0.0001283077,0.000202773,0.0003857698,0.0002317001,0.0002262874,0.0002315557,0.0004783914,0.0003337541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003357663,"about_ca_system_score_gemma":0.0002411346,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009448896,"about_ca_topic_score_gemma":0.001047212,"domain_scores_codex":[0.9998759,0.00001784954,0.000005980015,0.00003639521,0.00004038796,0.00002349748],"domain_scores_gemma":[0.9998004,0.00002561472,0.00006114792,0.00001606277,0.00003991224,0.00005683829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000787223,0.00008005993,0.06424081,0.0001110261,0.00006185743,0.0005567387,0.00006465563,0.0003641622,0.924433,0.0002061979,0.001239483,0.007854866],"study_design_scores_gemma":[0.00005813624,0.000902579,0.7306943,0.00002691675,0.00008022136,0.005498805,0.0002609324,0.007228328,0.2479679,0.0003829228,0.006863326,0.00003567666],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.993826,0.001181478,0.001631257,0.0002207331,0.0000331637,0.00002056259,0.001670496,0.0000801953,0.001336126],"genre_scores_gemma":[0.9969916,0.0002150606,0.000756072,0.00008086358,0.00002614899,0.00001205149,0.0009737486,0.00001262107,0.0009317924],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.002590992,"threshold_uncertainty_score":0.008667707,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06089445035445586,"score_gpt":0.4451585645729239,"score_spread":0.384264114218468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}