{"id":"W4393095547","doi":"10.1158/1538-7445.am2024-5063","title":"Abstract 5063: Exploring the mutational landscape of <i>KRAS</i> and <i>NRAS</i> in tumors with non-V600 <i>BRAF</i> mutations","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Neuroblastoma RAS viral oncogene homolog; KRAS; Biology; Cancer research; Cancer; Computational biology; Genetics; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000352129,0.0002001378,0.0004289215,0.0009407636,0.0002762274,0.0006214858,0.0002816694,0.0003080064,0.003399863],"category_scores_gemma":[0.0008657434,0.0001599958,0.0003477639,0.001272628,0.0001458928,0.0001657656,0.0003976806,0.0002469325,0.001412026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002285934,"about_ca_system_score_gemma":0.0002712945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002637094,"about_ca_topic_score_gemma":0.004938683,"domain_scores_codex":[0.9997062,0.00003913445,0.00002691273,0.0001393813,0.00004055323,0.0000478162],"domain_scores_gemma":[0.9994401,0.0001754441,0.0001329402,0.00008297904,0.00007049301,0.00009793961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001661321,0.00007247778,0.9369114,0.0002859917,0.0002027983,0.0009172572,0.0001746555,0.0008511074,0.02695115,0.000142821,0.006425072,0.02540384],"study_design_scores_gemma":[0.00005936208,0.0001867217,0.9822725,0.00003584028,0.0001571518,0.002665308,0.000234669,0.001228197,0.003856243,0.0002912854,0.009001215,0.00001164994],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9676862,0.0009828804,0.0006693109,0.0001206883,0.000009109901,0.00002342381,0.02909299,0.00007139231,0.001343973],"genre_scores_gemma":[0.9463004,0.0004017611,0.001125382,0.00009561847,0.00001973545,0.00003729754,0.05114203,0.00003958454,0.0008381002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003399863,"threshold_uncertainty_score":0.01137364,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04918132869603919,"score_gpt":0.3353208479138269,"score_spread":0.2861395192177877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}