{"id":"W4393098017","doi":"10.1111/cts.13758","title":"Ischemia‐induced cardiac dysfunction is exacerbated in adiponectin‐knockout mice due to impaired autophagy flux","year":2024,"lang":"en","type":"article","venue":"Clinical and Translational Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Autophagy; Adiponectin; Knockout mouse; Medicine; Cardiac dysfunction; Flux (metallurgy); Ischemia; Internal medicine; Myocardial ischemia; Cardiology; Biology; Heart failure; Obesity; Chemistry; Apoptosis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003019488,0.000797792,0.0004346336,0.0006236786,0.000223374,0.0004529812,0.0002746023,0.0004239504,0.002006751],"category_scores_gemma":[0.0001153813,0.0005385677,0.0003479954,0.0002861832,0.0004399112,0.0003326109,0.0002358824,0.001077039,0.0003322744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002147364,"about_ca_system_score_gemma":0.0001534251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000281061,"about_ca_topic_score_gemma":0.0005154929,"domain_scores_codex":[0.9998198,0.00002395945,0.00004068913,0.00005638319,0.00002698302,0.00003234185],"domain_scores_gemma":[0.9997497,0.00001864069,0.0001245186,0.00002495779,0.00001256896,0.00006965054],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005220573,0.00006145416,0.000484158,0.00005499891,0.00001935556,0.0001419751,0.000027924,0.00005972541,0.9975758,0.0000996638,0.00003617924,0.0009166494],"study_design_scores_gemma":[0.0003028666,0.001709585,0.06187502,0.00008966808,0.0002435136,0.002370992,0.0002089575,0.002711428,0.9268261,0.0004531708,0.003176332,0.00003235562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941994,0.0008727033,0.003658184,0.0001294116,0.00004080932,0.00002085629,0.0006196383,0.00009162198,0.0003675162],"genre_scores_gemma":[0.9919696,0.00108767,0.003073403,0.0001265845,0.00002160649,0.00009072888,0.0007200929,0.00004478983,0.002865491],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002006751,"threshold_uncertainty_score":0.006713212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04018694975019829,"score_gpt":0.3674862841051378,"score_spread":0.3272993343549395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}