{"id":"W4393157924","doi":"10.1111/cpr.13618","title":"Rack1‐mediated ferroptosis affects hindgut development in rats with anorectal malformations: Spatial transcriptome insights","year":2024,"lang":"en","type":"article","venue":"Cell Proliferation","topic":"Congenital gastrointestinal and neural anomalies","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Shengjing Hospital; National Natural Science Foundation of China","keywords":"Hindgut; Transcriptome; Cell biology; Biology; MAPK/ERK pathway; p38 mitogen-activated protein kinases; Downregulation and upregulation; Signal transduction; Gene expression; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007438097,0.0001857647,0.0001900057,0.0002629244,0.00007307633,0.00008293925,0.00004020689,0.00005810743,0.00005959691],"category_scores_gemma":[0.00002015385,0.0001305763,0.00003857859,0.0003462055,0.00003367837,0.0003335495,0.00001250248,0.000213066,0.0001130704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009624103,"about_ca_system_score_gemma":0.0002055527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001400544,"about_ca_topic_score_gemma":0.0002822333,"domain_scores_codex":[0.9990118,0.00003751599,0.00025817,0.0002485149,0.0002422111,0.0002018457],"domain_scores_gemma":[0.9996907,0.00003435181,0.00003131981,0.00008080895,0.00006790284,0.00009495707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002540012,0.0007668838,0.04771257,0.002316216,0.0001001106,0.001084237,0.01275845,0.0001162487,0.8884225,0.0001259993,0.0004570909,0.04359962],"study_design_scores_gemma":[0.003422444,0.002672883,0.1133813,0.001681799,0.0001456848,0.0007905659,0.000366237,0.03329428,0.8385673,0.00004897734,0.004934552,0.000693959],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958829,0.00060068,0.0008448272,0.0005146946,0.0001227275,0.000747735,0.000002762678,0.0001547037,0.001128944],"genre_scores_gemma":[0.9977303,0.00001938026,0.0005690188,0.0001533304,0.0001061472,0.0001293253,0.0001817249,0.00002043695,0.001090401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06566873,"threshold_uncertainty_score":0.5324746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01147909823237692,"score_gpt":0.2162390138081811,"score_spread":0.2047599155758042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}