{"id":"W4393164267","doi":"10.1093/pnasnexus/pgae126","title":"Host–microbiome associations in saliva predict COVID-19 severity","year":2024,"lang":"en","type":"article","venue":"PNAS Nexus","topic":"Salivary Gland Disorders and Functions","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Dental and Craniofacial Research; National Institutes of Health; National Institute of Allergy and Infectious Diseases; L'Oreal USA; Dasman Diabetes Institute; Conrad Prebys Foundation","keywords":"Coronavirus disease 2019 (COVID-19); Microbiome; Saliva; 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Host (biology); Biology; Medicine; Virology; Bioinformatics; Genetics; Internal medicine; Outbreak; Infectious disease (medical specialty); Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001961692,0.0001148541,0.000191064,0.0002139801,0.00008789864,0.00004682829,0.00005422794,0.0001119746,0.0007819665],"category_scores_gemma":[0.0003501318,0.0001018386,0.00009595211,0.0006117583,0.00004003336,0.00009624194,0.0000314987,0.0002212658,0.0002499491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002539657,"about_ca_system_score_gemma":0.0004022148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008194854,"about_ca_topic_score_gemma":0.0002267487,"domain_scores_codex":[0.9991174,0.00003723027,0.0002101551,0.0002566849,0.0001448366,0.0002337175],"domain_scores_gemma":[0.999395,0.0001670381,0.00002274746,0.0001944045,0.00002681758,0.0001939598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001965123,0.0009882916,0.5416695,0.0005849591,0.0003509486,0.0007495105,0.004782408,0.00007639947,0.003766403,0.00608567,0.4387688,0.001980508],"study_design_scores_gemma":[0.002681876,0.0002607134,0.4903615,0.0001353559,0.0002356621,0.0002169989,0.0007028246,0.002572282,0.00009229178,0.004802085,0.4975924,0.0003459856],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7544789,0.01301129,0.006532876,0.06415335,0.004888829,0.002068544,0.001621957,0.002239051,0.1510052],"genre_scores_gemma":[0.9915032,0.00009340148,0.00013153,0.003303767,0.0002644926,0.00003755974,0.0003324688,0.00002250206,0.004311025],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2370243,"threshold_uncertainty_score":0.8561985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02899510129931288,"score_gpt":0.3161668799238265,"score_spread":0.2871717786245136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}