{"id":"W4393164267","doi":"10.1093/pnasnexus/pgae126","title":"Host–microbiome associations in saliva predict COVID-19 severity","year":2024,"lang":"en","type":"article","venue":"PNAS Nexus","topic":"Salivary Gland Disorders and Functions","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Dental and Craniofacial Research; National Institutes of Health; National Institute of Allergy and Infectious Diseases; L'Oreal USA; Dasman Diabetes Institute; Conrad Prebys Foundation","keywords":"Coronavirus disease 2019 (COVID-19); Microbiome; Saliva; 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Host (biology); Biology; Medicine; Virology; Bioinformatics; Genetics; Internal medicine; Outbreak; Infectious disease (medical specialty); Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004900913,0.000410773,0.0004927041,0.000782492,0.0003523237,0.0008453557,0.0001179419,0.0004091407,0.001760259],"category_scores_gemma":[0.0009596605,0.0001721645,0.0004194661,0.0005399961,0.0002089869,0.000347778,0.0007414179,0.0005025884,0.0002453054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001676534,"about_ca_system_score_gemma":0.0001689948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007399836,"about_ca_topic_score_gemma":0.0009875539,"domain_scores_codex":[0.9997115,0.00007292995,0.00004002124,0.00005942041,0.00005874393,0.00005739162],"domain_scores_gemma":[0.999386,0.00009355861,0.0002936613,0.00003027736,0.00009176916,0.0001048215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004184584,0.00004716753,0.9842079,0.00003244756,0.00006622887,0.00008494472,0.00006328246,0.00008339785,0.01103409,0.0000139824,0.00008793862,0.00386014],"study_design_scores_gemma":[0.000003883415,0.0001887623,0.9969282,0.00001255933,0.00003326719,0.0002799379,0.0002431505,0.0006471078,0.001438571,0.00004876878,0.0001701268,0.000005737258],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983503,0.0006714729,0.0002997601,0.00002908569,0.000008559075,0.00001604969,0.0003164087,0.00000776675,0.0003005779],"genre_scores_gemma":[0.9990807,0.0001573991,0.0003577782,0.00001354256,0.000007739945,0.000009861078,0.0002289879,0.000001553929,0.0001424378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001760259,"threshold_uncertainty_score":0.0058887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02899510129931288,"score_gpt":0.3161668799238265,"score_spread":0.2871717786245136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}