{"id":"W4393167835","doi":"10.1016/j.jbc.2024.106685","title":"Abstract 1725 ER-PM membrane contact sites promote nuclear segregation in budding yeast","year":2024,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Institute of General Medical Sciences; University of Texas Southwestern Medical Center","keywords":"Budding yeast; Budding; Yeast; Cell biology; Inner membrane; Chemistry; Saccharomyces cerevisiae; Nuclear pore; Membrane; Biology; Biophysics; Biochemistry; Nucleus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002284043,0.0001302815,0.0001709285,0.00003045752,0.00003016174,0.00005191201,0.0001305225,0.0002815769,0.0003439573],"category_scores_gemma":[0.0001251936,0.00009305856,0.0001318538,0.0000877034,0.00003843562,0.00001390049,0.00003853775,0.000314351,0.00001057335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003196206,"about_ca_system_score_gemma":0.00003599781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002894703,"about_ca_topic_score_gemma":0.000001205088,"domain_scores_codex":[0.9992031,0.00001806423,0.0003180244,0.0001968694,0.0001084585,0.0001555027],"domain_scores_gemma":[0.9996364,0.00001446585,0.0001217054,0.00010216,0.00005557461,0.00006971323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001583715,0.00003093893,0.0004833934,0.00006247411,0.00003983912,0.00006133765,0.00002463267,0.00001300147,0.9949996,0.00002589409,0.0006554421,0.00344502],"study_design_scores_gemma":[0.000506581,0.0003543729,0.01253324,0.000174458,0.00002294812,0.0004600767,0.0001265128,0.00009111091,0.9489388,0.0003819709,0.03617996,0.0002299746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969559,0.0008327654,0.0000180192,0.0001860581,0.0001612684,0.00004246805,0.000008846148,0.00001275958,0.001781923],"genre_scores_gemma":[0.9986027,0.0002880494,0.000258028,0.0000852935,0.0006321069,6.927885e-7,0.00003443995,0.00001392541,0.00008473334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04606086,"threshold_uncertainty_score":0.3794818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01294646739208684,"score_gpt":0.2419828504280827,"score_spread":0.2290363830359958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}