{"id":"W4393194691","doi":"10.1016/j.cgh.2024.01.034","title":"Commentary: Liquid Biopsy for Average-Risk Colorectal Cancer Screening","year":2024,"lang":"en","type":"article","venue":"Clinical Gastroenterology and Hepatology","topic":"Colorectal Cancer Screening and Detection","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Argonne National Laboratory; National Cancer Institute; Department of Internal Medicine, University of Utah; U.S. Public Health Service; Memorial Sloan-Kettering Cancer Center; University of Minnesota; University of California, Los Angeles; NYU Grossman School of Medicine; University of California, San Diego; School of Medicine, Stanford University; Genentech; Massachusetts General Hospital; York University; University of Pennsylvania; Masonic Cancer Center, University of Minnesota; American Gastroenterological Association; Ohio State University; U.S. Department of Veterans Affairs","keywords":"Medicine; Liquid biopsy; Colorectal cancer; Oncology; Biopsy; Internal medicine; Colonoscopy; Colorectal cancer screening; Cancer","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005596044,0.0001798648,0.0005681399,0.0001198591,0.0001465635,0.00001653996,0.00006380394,0.0002965359,0.0001014377],"category_scores_gemma":[0.0001297318,0.0001562667,0.0002430741,0.00008346169,0.0004189101,0.00004817259,0.00008095779,0.0006282364,0.000007253611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003844896,"about_ca_system_score_gemma":0.00005482052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001904743,"about_ca_topic_score_gemma":0.0005169893,"domain_scores_codex":[0.9982924,0.0002031452,0.0004849042,0.0005526496,0.00006514325,0.0004017907],"domain_scores_gemma":[0.9989324,0.0005952499,0.00008772988,0.0001274018,0.0000580285,0.0001991878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.05279633,0.0001123324,0.9117241,0.0001007427,0.0005598573,0.0001057382,0.00007025125,0.000005131663,0.0001554209,0.00007749175,0.01039821,0.02389441],"study_design_scores_gemma":[0.01502565,0.1264855,0.6460903,0.0004781226,0.002314775,0.004751864,0.0001627135,0.06669035,0.0008713583,0.0006815856,0.1358917,0.0005561985],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9622113,0.001415744,0.01838481,0.01569226,0.001634208,0.0003587934,0.00007407665,0.0001776543,0.00005121431],"genre_scores_gemma":[0.988697,0.0008127778,0.001843334,0.007614002,0.0007310067,0.0001749918,0.0000442459,0.00002527731,0.00005737995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2656338,"threshold_uncertainty_score":0.6372373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03535403489199842,"score_gpt":0.3607126877893221,"score_spread":0.3253586528973237,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}