{"id":"W4393194691","doi":"10.1016/j.cgh.2024.01.034","title":"Commentary: Liquid Biopsy for Average-Risk Colorectal Cancer Screening","year":2024,"lang":"en","type":"article","venue":"Clinical Gastroenterology and Hepatology","topic":"Colorectal Cancer Screening and Detection","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Argonne National Laboratory; National Cancer Institute; Department of Internal Medicine, University of Utah; U.S. Public Health Service; Memorial Sloan-Kettering Cancer Center; University of Minnesota; University of California, Los Angeles; NYU Grossman School of Medicine; University of California, San Diego; School of Medicine, Stanford University; Genentech; Massachusetts General Hospital; York University; University of Pennsylvania; Masonic Cancer Center, University of Minnesota; American Gastroenterological Association; Ohio State University; U.S. Department of Veterans Affairs","keywords":"Medicine; Liquid biopsy; Colorectal cancer; Oncology; Biopsy; Internal medicine; Colonoscopy; Colorectal cancer screening; Cancer","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006975531,0.001594443,0.002590001,0.001946224,0.003869446,0.003599738,0.004630769,0.06749717,0.01131114],"category_scores_gemma":[0.06963081,0.001311043,0.002320418,0.001793686,0.003718395,0.004690826,0.002172723,0.05960068,0.00761042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005605793,"about_ca_system_score_gemma":0.00771642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01069254,"about_ca_topic_score_gemma":0.01502544,"domain_scores_codex":[0.9934321,0.002067571,0.00100689,0.0009541326,0.001902733,0.0006365478],"domain_scores_gemma":[0.9431373,0.03571503,0.002900993,0.0008682258,0.01250957,0.004868982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006699321,0.00001213911,0.0002063467,0.0001785623,0.00002955187,0.0001605262,0.00003364597,0.00003826204,0.00007944791,0.0006123225,0.9942305,0.004351716],"study_design_scores_gemma":[0.0003749602,0.0001457648,0.002220139,0.002503645,0.0003468354,0.001143965,0.0004105237,0.0006302019,0.0004431549,0.006274541,0.9853478,0.0001583623],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0001755695,0.002373805,0.00008122762,0.8862033,0.1098342,0.00001673166,0.000135933,0.00002199875,0.001157236],"genre_scores_gemma":[0.002024352,0.001343829,0.000196562,0.8524778,0.1419758,0.00003842201,0.00005436276,0.0000204138,0.001868331],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.06749717,"threshold_uncertainty_score":0.04067302,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03535403489199842,"score_gpt":0.3607126877893221,"score_spread":0.3253586528973237,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}