{"id":"W4393196520","doi":"10.1002/imt2.181","title":"<i>Lactobacillus rhamnosus</i> GG triggers intestinal epithelium injury in zebrafish revealing host dependent beneficial effects","year":2024,"lang":"en","type":"article","venue":"iMeta","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Chinese Academy of Agricultural Sciences; China Scholarship Council; Agricultural Science and Technology Innovation Program; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Pyroptosis; Zebrafish; Lactobacillus rhamnosus; Intestinal epithelium; Biology; Dysbiosis; Probiotic; Microbiology; Cell biology; Epithelium; Inflammasome; Immunology; Gut flora; Inflammation; Bacteria; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000368733,0.0002467855,0.0002346736,0.0001469826,0.00006215868,0.00008503166,0.0002497962,0.0001853786,0.00002763724],"category_scores_gemma":[0.0002076579,0.0002368261,0.0001718697,0.0002456712,0.00005895035,0.00001280124,0.0001425996,0.0002622368,0.00008418772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003553893,"about_ca_system_score_gemma":0.0001278263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001146863,"about_ca_topic_score_gemma":0.00007690872,"domain_scores_codex":[0.9985139,0.00009380675,0.0003363947,0.0004762677,0.0001670992,0.0004125331],"domain_scores_gemma":[0.9994704,0.00004050734,0.00005213436,0.0003272638,0.0000462092,0.00006349608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002118227,0.00006907454,0.001138709,0.0001432247,0.0001003912,0.00008023764,0.0001205926,0.00004084434,0.9794375,0.0001195595,0.001517907,0.01702014],"study_design_scores_gemma":[0.0007850616,0.0004616991,0.002347353,0.0001881317,0.0000661281,0.00003908395,0.00009076444,0.0001359699,0.9600513,0.0001331208,0.03523333,0.0004680694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904042,0.005514823,0.0003935538,0.0002350366,0.0009328078,0.000293507,0.00002625113,0.00004396995,0.002155838],"genre_scores_gemma":[0.998219,0.0002746706,0.0001722258,0.000390734,0.0002422719,0.00003375868,0.0001075612,0.00004462835,0.000515202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03371542,"threshold_uncertainty_score":0.9657489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004952540019701935,"score_gpt":0.2371386720292639,"score_spread":0.2321861320095619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}