{"id":"W4393226480","doi":"10.1080/1744666x.2024.2326626","title":"Tumor associated macrophages as key contributors and targets in current and future therapies for melanoma","year":2024,"lang":"en","type":"review","venue":"Expert Review of Clinical Immunology","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Thomas Hospital","funders":"King's Health Partners; King's College London; Breast Cancer Now; Department of Health and Social Care; King’s College London; Cancer Research UK; Medical Research Council; British Skin Foundation; National Institute for Health and Care Research; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research; Wellcome Trust; Wellcome","keywords":"Melanoma; Immune system; Medicine; Tumor microenvironment; Immunotherapy; Immunology; Cancer research; Macrophage; Cancer; Metastasis; Biology; Internal medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007626271,0.0005892116,0.0009920185,0.00150429,0.0002155906,0.000959859,0.0007138147,0.00135951,0.005104834],"category_scores_gemma":[0.0009670911,0.0001912407,0.0005796963,0.001115668,0.0004171955,0.001341354,0.0006352388,0.002137829,0.00202904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000564658,"about_ca_system_score_gemma":0.001170638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006587643,"about_ca_topic_score_gemma":0.001416794,"domain_scores_codex":[0.9997271,0.00006608912,0.00003110833,0.00004266384,0.0001007978,0.00003227255],"domain_scores_gemma":[0.9995602,0.0002221668,0.00005795501,0.000008916571,0.0001172818,0.00003350949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001071278,0.00004785067,0.0001323595,0.02342172,0.00007557985,0.000143875,0.00006178881,0.0002555539,0.001783884,0.004360251,0.05131807,0.9182919],"study_design_scores_gemma":[0.00002551534,0.0001248208,0.0004690934,0.00770687,0.0001158505,0.0008074315,0.0000597198,0.00007110255,0.0004146115,0.002316778,0.9878733,0.00001504317],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005271038,0.9985862,0.00007086871,0.0004901424,0.0003078887,0.00000386634,0.00001205095,0.000004622794,0.0004717729],"genre_scores_gemma":[0.0005509023,0.9980717,0.0001138793,0.0004594547,0.0003270289,0.000006409793,0.00002464929,0.000001428508,0.0004444923],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005104834,"threshold_uncertainty_score":0.01707739,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04041114205051054,"score_gpt":0.4348291951254526,"score_spread":0.3944180530749421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}