{"id":"W4393233240","doi":"10.1186/s13068-024-02491-8","title":"Substrate specificity mapping of fungal CAZy AA3_2 oxidoreductases","year":2024,"lang":"en","type":"article","venue":"Biotechnology for Biofuels and Bioproducts","topic":"Enzyme-mediated dye degradation","field":"Agricultural and Biological Sciences","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University; University of Toronto","funders":"Suomen Kulttuurirahasto; Novo Nordisk; Novo Nordisk Fonden; Academy of Finland; Helsingin ja Uudenmaan Sairaanhoitopiiri; Helsingin Yliopisto","keywords":"Subfamily; Biochemistry; Biology; Enzyme; Homology (biology); Amino acid; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001930946,0.0004246609,0.0002109134,0.0006444013,0.0001488213,0.0003253952,0.000194336,0.0002214172,0.0005836489],"category_scores_gemma":[0.0003106185,0.00008952298,0.0004270725,0.001033629,0.0001078743,0.0001898571,0.0002174718,0.0003005436,0.0003662753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003123373,"about_ca_system_score_gemma":0.0002459921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001507461,"about_ca_topic_score_gemma":0.001104711,"domain_scores_codex":[0.9998264,0.0000184939,0.00001955541,0.00006427571,0.00004250931,0.00002873355],"domain_scores_gemma":[0.9998178,0.00003938674,0.00005612326,0.00001521913,0.00004624254,0.00002523224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003486333,0.00005693419,0.005914227,0.000119708,0.00002049168,0.00009003896,0.00006634492,0.0004801265,0.9847767,0.0001068902,0.00005628242,0.007963493],"study_design_scores_gemma":[0.00003190011,0.0003482334,0.1029929,0.00004577225,0.0001048741,0.001402383,0.0002167745,0.01158141,0.8764549,0.0002467871,0.006552581,0.00002141161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876507,0.001038697,0.008187895,0.00004088857,0.000007305436,0.00005519539,0.001885546,0.00004743845,0.001086337],"genre_scores_gemma":[0.9747012,0.0007122821,0.01705291,0.00002353864,0.000006332392,0.00004899721,0.006810467,0.00002092614,0.000623389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001507461,"threshold_uncertainty_score":0.002997398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02479066447960737,"score_gpt":0.2197193313722801,"score_spread":0.1949286668926727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}