{"id":"W4393235420","doi":"10.21203/rs.3.rs-4151642/v1","title":"High throughput rapid amplicon sequencing for multilocus sequence typing of M. ovipneumoniae using DNA obtained from clinical samples","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Microbial infections and disease research","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Public Health Agency of Canada","funders":"Foundation for North American Wild Sheep","keywords":"Amplicon; Multilocus sequence typing; Biology; DNA sequencing; Typing; Computational biology; Genetics; Sequence (biology); DNA; Polymerase chain reaction; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001084403,0.0004595731,0.000412133,0.0008771811,0.000293893,0.0007598121,0.0003957523,0.0006093529,0.0008069909],"category_scores_gemma":[0.001777368,0.0002467442,0.0004819119,0.000432149,0.0002743427,0.0004660529,0.0005253064,0.0003639088,0.0006890016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003928592,"about_ca_system_score_gemma":0.0006053789,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006040222,"about_ca_topic_score_gemma":0.00131693,"domain_scores_codex":[0.9986144,0.000311183,0.0001556662,0.0003569999,0.0004688808,0.00009273658],"domain_scores_gemma":[0.9988375,0.0004040175,0.0001913313,0.0001252039,0.0003637977,0.00007814189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003132735,0.0001222507,0.007031195,0.000407115,0.0000587088,0.0001646962,0.0001420712,0.002110502,0.9422438,0.0002831878,0.0006963845,0.04642678],"study_design_scores_gemma":[0.00003460948,0.0006024818,0.01873609,0.0001143721,0.0001054078,0.001009112,0.0001734063,0.0417232,0.9284177,0.0007725919,0.008227753,0.00008326266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.5133871,0.003353483,0.4722498,0.0005539036,0.0002574575,0.0009355306,0.003815691,0.002956288,0.002490693],"genre_scores_gemma":[0.6048411,0.00133702,0.3873476,0.0003930567,0.00008648872,0.0006209661,0.003525119,0.0001272972,0.001721479],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001084403,"threshold_uncertainty_score":0.005734921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.293975941238922,"score_gpt":0.4803701093269092,"score_spread":0.1863941680879872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}