{"id":"W4393254619","doi":"10.1038/s41564-024-01672-3","title":"Crimean–Congo haemorrhagic fever virus uses LDLR to bind and enter host cells","year":2024,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"Viral Infections and Vectors","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Horizon 2020 Framework Programme; National Institutes of Health; Vetenskapsrådet; Svenska Sällskapet för Medicinsk Forskning; Università degli Studi di Padova; Karolinska Institutet; Division of Intramural Research, National Institute of Allergy and Infectious Diseases; European Commission; Texas Biomedical Research Institute","keywords":"LDL receptor; Virology; Biology; Glycoprotein; Virus; Antibody; Population; Receptor; Lipoprotein; Immunology; Molecular biology; Medicine; Cholesterol; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001781673,0.0002539193,0.0001681221,0.0002162459,0.0003216983,0.0005657034,0.0001338298,0.0002890542,0.00104038],"category_scores_gemma":[0.0001305155,0.00008076783,0.000250823,0.00009144681,0.0002242512,0.0002215828,0.000333771,0.0002717807,0.0003365988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004151058,"about_ca_system_score_gemma":0.0001643609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002893078,"about_ca_topic_score_gemma":0.002777783,"domain_scores_codex":[0.9998367,0.00005288542,0.00001114398,0.00002493394,0.00002966241,0.00004475112],"domain_scores_gemma":[0.9999312,0.00001471797,0.00002452868,0.00001075307,0.000009407624,0.000009305741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001340142,0.00003044534,0.006854645,0.0001533675,0.00003737765,0.0004638039,0.0001160533,0.0001661056,0.9808561,0.0007066386,0.0003396676,0.01014168],"study_design_scores_gemma":[0.00002303605,0.0004800321,0.1080642,0.00008306643,0.00006176771,0.006021948,0.0007009413,0.002230208,0.8475609,0.0002889104,0.03443466,0.00005033378],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859876,0.005011808,0.003183318,0.0003570085,0.00004086767,0.00002706779,0.0003232339,0.00004739431,0.005021781],"genre_scores_gemma":[0.9943903,0.001396934,0.001719976,0.0001129152,0.00001126501,0.00001527599,0.0002694701,0.000004959548,0.002078834],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002893078,"threshold_uncertainty_score":0.005752504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008043954589986675,"score_gpt":0.2860265110184599,"score_spread":0.2779825564284732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}