{"id":"W4393281294","doi":"10.21037/jtd-24-188","title":"The role and mechanism of PDZ binding kinase in hypobaric and hypoxic acute lung injury","year":2024,"lang":"en","type":"article","venue":"Journal of Thoracic Disease","topic":"High Altitude and Hypoxia","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Tianjin Medical University","keywords":"Medicine; PDZ domain; Mechanism (biology); Kinase; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002309777,0.0004402039,0.0004096483,0.0004288433,0.0004156198,0.0005473522,0.0004320512,0.0005269292,0.00128051],"category_scores_gemma":[0.0001185211,0.0001523911,0.0005359185,0.0001981476,0.0005212635,0.0005384657,0.0004838509,0.0007992274,0.0002509108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005780766,"about_ca_system_score_gemma":0.0003465906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000462472,"about_ca_topic_score_gemma":0.0003625709,"domain_scores_codex":[0.9998683,0.00001982759,0.00001052002,0.00002990718,0.00002603438,0.00004545668],"domain_scores_gemma":[0.999926,0.000004868898,0.00002983546,0.000004491629,0.00001219585,0.00002276226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004841633,0.001014691,0.0143893,0.004709668,0.0003046239,0.003295825,0.0003550075,0.001984217,0.865509,0.01439765,0.006369263,0.08282917],"study_design_scores_gemma":[0.001032412,0.003626318,0.1525263,0.0004393458,0.0006843362,0.01063471,0.001036507,0.01528399,0.7145683,0.01106633,0.08895016,0.0001514115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7771991,0.1910784,0.01656507,0.003344183,0.000748839,0.0002920776,0.00129637,0.0002911864,0.009184804],"genre_scores_gemma":[0.9734301,0.02136145,0.001454374,0.0004015816,0.00009320993,0.0001127131,0.0005642553,0.00000646883,0.002575835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00128051,"threshold_uncertainty_score":0.004283726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005080981830241727,"score_gpt":0.2842194445612797,"score_spread":0.2791384627310379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}