{"id":"W4393307842","doi":"10.1158/1078-0432.ccr-23-3840","title":"Solid Organ Transplant Recipients Exhibit More <i>TET2</i> -Mutant Clonal Hematopoiesis of Indeterminate Potential Not Driven by Increased Transplantation Risk","year":2024,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; Vanderbilt University Medical Center; NIH Office of the Director; National Institute for Occupational Safety and Health; Centers for Disease Control and Prevention; National Cancer Institute; National Institutes of Health; Edward P. Evans Foundation; Canadian Institutes of Health Research; Leukemia and Lymphoma Society; Burroughs Wellcome Fund","keywords":"Transplantation; Population; Biobank; Malignancy; Haematopoiesis; Internal medicine; Biology; Oncology; Medicine; Immunology; Bioinformatics; Genetics; Stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004337834,0.0001469431,0.0001791053,0.0003504172,0.0002214113,0.0004910401,0.0002020366,0.0001792369,0.002415451],"category_scores_gemma":[0.001062911,0.00006867375,0.0001337033,0.0004645681,0.0002059281,0.0002010935,0.0003101545,0.00027623,0.0002303744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001737587,"about_ca_system_score_gemma":0.0001751692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005984509,"about_ca_topic_score_gemma":0.0008438939,"domain_scores_codex":[0.9997684,0.00004862134,0.0000249811,0.00006316383,0.00005581322,0.00003903565],"domain_scores_gemma":[0.9991164,0.0001392179,0.0004875932,0.0001042011,0.00005496017,0.000097738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003378099,0.00006848796,0.9769855,0.00003071149,0.00003750931,0.0001204869,0.00007525268,0.0001005321,0.0152135,0.0001064875,0.0001717838,0.006752057],"study_design_scores_gemma":[0.00001408933,0.0002158687,0.9939945,0.000006674135,0.00003579489,0.001051941,0.00009883954,0.0002401777,0.00372909,0.0001286278,0.0004807204,0.000003660802],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99913,0.00008314798,0.0002228849,0.00002938599,0.000001491486,0.000005087377,0.0001853843,0.000009785791,0.0003327845],"genre_scores_gemma":[0.9993868,0.00003251971,0.0001811669,0.0000288995,0.000004149669,0.000004586033,0.0002580948,0.000001914095,0.0001018439],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002415451,"threshold_uncertainty_score":0.008080482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06296916830744788,"score_gpt":0.4658679497737175,"score_spread":0.4028987814662697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}