{"id":"W4393321517","doi":"10.1016/j.bea.2024.100120","title":"Immobilization of novel synthesized phosphobetaine zwitterions on polyethersulphone (PES) hemodialysis membranes to induce hemocompatibility: Experimental, molecular docking, and ex-vivo inflammatory biomarker investigations","year":2024,"lang":"en","type":"article","venue":"Biomedical Engineering Advances","topic":"Polymer Surface Interaction Studies","field":"Materials Science","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Saskatchewan Health Research Foundation","keywords":"Membrane; Zwitterion; Chemistry; Fibrinogen; Ex vivo; Docking (animal); Pharmacology; Combinatorial chemistry; Biochemistry; Organic chemistry; Medicine; In vitro; Molecule","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001764205,0.0003735557,0.0001237955,0.0001137849,0.00007662358,0.0001219796,0.0001718481,0.0002907992,0.0004575913],"category_scores_gemma":[0.0002072354,0.0001171437,0.0001631138,0.0001038752,0.0001049657,0.0002433544,0.0001504206,0.000211986,0.0001328596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001280851,"about_ca_system_score_gemma":0.00008355793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001765397,"about_ca_topic_score_gemma":0.0002204541,"domain_scores_codex":[0.9999267,0.00001110761,0.000007342944,0.0000170653,0.00002321981,0.000014483],"domain_scores_gemma":[0.9999213,0.00001366108,0.00003609303,0.000006512536,0.00001383191,0.00000854943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002169361,0.000009030317,0.00004112122,0.00002277004,0.000002541791,0.00002012782,0.000009885624,0.00005105748,0.9992397,0.00002269102,0.000006570147,0.000552939],"study_design_scores_gemma":[0.000003986411,0.0001357007,0.0004787596,0.000001842411,0.000004221538,0.00003996721,0.000007118172,0.0002286941,0.99878,0.000006312717,0.0003117592,0.000001777958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965039,0.0003843669,0.002655213,0.00002638818,0.000008690097,0.00002339735,0.00004682293,0.00002202883,0.0003292095],"genre_scores_gemma":[0.9930693,0.0006556125,0.005059326,0.0000208244,0.000004850947,0.00004947759,0.00008409898,0.00001146176,0.00104512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004575913,"threshold_uncertainty_score":0.001530766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01612265419960297,"score_gpt":0.2807095238947246,"score_spread":0.2645868696951217,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}