{"id":"W4393334467","doi":"10.1093/nar/gkae199","title":"Critical steps in the assembly process of the bacterial 50S ribosomal subunit","year":2024,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft; California Department of Fish and Game","keywords":"Ribosome; Biology; Bacillus subtilis; Protein subunit; Ribosomal RNA; 50S; Ribosomal protein; Eukaryotic Ribosome; Bacteria; Computational biology; Bacterial protein; Cell biology; Biochemistry; Genetics; Gene; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004783146,0.0007992618,0.0005627965,0.0008726074,0.0007204621,0.000974787,0.000543765,0.0009467004,0.001213341],"category_scores_gemma":[0.0005679565,0.0005694792,0.0005917103,0.0004608035,0.0009105612,0.001404567,0.0007962632,0.001017386,0.001355144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007874442,"about_ca_system_score_gemma":0.000884257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008513799,"about_ca_topic_score_gemma":0.0007407051,"domain_scores_codex":[0.9995071,0.00007368454,0.00005469877,0.0001128157,0.0001763895,0.00007533422],"domain_scores_gemma":[0.9997279,0.00008386354,0.00007982985,0.00001388238,0.00005538402,0.00003912758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004507027,0.00006932194,0.002070271,0.007704183,0.0001207278,0.002574784,0.001492636,0.004042349,0.8124012,0.054125,0.00202371,0.1129251],"study_design_scores_gemma":[0.00002876449,0.0005393199,0.01513288,0.001592774,0.0001784959,0.002756211,0.0009964377,0.002065077,0.7231919,0.02345385,0.229923,0.0001413949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.217993,0.6575288,0.08091226,0.001532434,0.001054873,0.0003019175,0.0005936714,0.0007673558,0.03931575],"genre_scores_gemma":[0.5446661,0.3918663,0.05035557,0.0004538939,0.000321082,0.0002332885,0.000686642,0.000145341,0.01127192],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001213341,"threshold_uncertainty_score":0.005713284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03826488673123989,"score_gpt":0.3641953904927044,"score_spread":0.3259305037614645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}