{"id":"W4393338299","doi":"10.1016/j.virusres.2024.199366","title":"Increased GABA signaling in liver macrophage promotes HBV replication in HBV-carrier mice","year":2024,"lang":"en","type":"article","venue":"Virus Research","topic":"GABA and Rice Research","field":"Agricultural and Biological Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Shandong First Medical University; Natural Science Foundation of Shandong Province; National Natural Science Foundation of China","keywords":"Biology; Cell biology; Macrophage; Immune system; Receptor; Signal transduction; Viral replication; Virology; Immunology; Virus; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001644172,0.0003332724,0.0002775495,0.0005709635,0.0001842796,0.0002633297,0.0001432021,0.0004522654,0.002031002],"category_scores_gemma":[0.0001131179,0.0002178493,0.0002630815,0.0001725475,0.0002550988,0.0003017569,0.0002465406,0.0008691777,0.0005669768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000250478,"about_ca_system_score_gemma":0.000139255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000321374,"about_ca_topic_score_gemma":0.0004143967,"domain_scores_codex":[0.9998655,0.0000290705,0.0000180448,0.0000286434,0.00002114638,0.00003766501],"domain_scores_gemma":[0.9998282,0.00002047127,0.00005885869,0.00001199702,0.00001173347,0.00006868336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005520523,0.0000566387,0.0005146728,0.00004222056,0.000005904269,0.0001319739,0.00003920558,0.00002058926,0.9963446,0.0001292825,0.00004575426,0.002116954],"study_design_scores_gemma":[0.0001747148,0.001916457,0.01903332,0.00004476985,0.00006609201,0.001153545,0.0001695663,0.0007336109,0.9713,0.0004004118,0.004989832,0.00001764602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924985,0.003252758,0.001818278,0.0003233519,0.00005086187,0.00002570568,0.000311249,0.0001589351,0.00156035],"genre_scores_gemma":[0.9888315,0.002572122,0.003001582,0.0002070353,0.00006036534,0.00008000334,0.0003708756,0.00009537535,0.004781093],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002031002,"threshold_uncertainty_score":0.006794393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.098307623021908,"score_gpt":0.3642066545682743,"score_spread":0.2658990315463663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}