{"id":"W4393378386","doi":"10.3390/vaccines12040375","title":"Mucosal Immunization with Spore-Based Vaccines against Mannheimia haemolytica Enhances Antigen-Specific Immunity","year":2024,"lang":"en","type":"article","venue":"Vaccines","topic":"Microbial infections and disease research","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of British Columbia; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; Alberta Beef Producers; Results Driven Agriculture Research","keywords":"Nasal administration; Antigen; Immunogenicity; Microbiology; Adjuvant; Immunology; Immunization; Antibody; Vaccination; Cholera toxin; Immunoglobulin A; Biology; Virology; Immunoglobulin G","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002507593,0.0003025196,0.0003087201,0.0004205683,0.0004925317,0.0002065857,0.0002845862,0.0002009856,0.002599076],"category_scores_gemma":[0.00003284291,0.000225253,0.0001311531,0.0008119996,0.0001000791,0.0002440807,0.00008943735,0.0003954369,0.001044308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005462951,"about_ca_system_score_gemma":0.0002272576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001973739,"about_ca_topic_score_gemma":0.00009813676,"domain_scores_codex":[0.9984925,0.0001868168,0.0003346762,0.0004444486,0.00006126084,0.0004802373],"domain_scores_gemma":[0.9989566,0.0001753261,0.00006275452,0.0005153953,0.0002386873,0.00005126472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007477905,0.0004469754,0.006184008,0.0001872436,0.0004050589,0.00008018511,0.0001892853,0.0001665581,0.9513994,0.00165325,0.02216488,0.01637536],"study_design_scores_gemma":[0.002461286,0.000468264,0.03257712,0.0005413488,0.00009205408,0.000147026,0.0004054568,0.0003520889,0.60018,0.0001719909,0.3617436,0.0008597364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9704458,0.02408045,0.001610144,0.0006319224,0.0008338645,0.0003983101,0.0000575255,0.0004321575,0.001509861],"genre_scores_gemma":[0.9946724,0.002739453,0.000116542,0.00008540674,0.0001372233,0.00003968195,0.0007246408,0.00005047056,0.00143419],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3512194,"threshold_uncertainty_score":0.9997335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01464205355713585,"score_gpt":0.2620174229085237,"score_spread":0.2473753693513878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}