{"id":"W4393378386","doi":"10.3390/vaccines12040375","title":"Mucosal Immunization with Spore-Based Vaccines against Mannheimia haemolytica Enhances Antigen-Specific Immunity","year":2024,"lang":"en","type":"article","venue":"Vaccines","topic":"Microbial infections and disease research","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of British Columbia; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; Alberta Beef Producers; Results Driven Agriculture Research","keywords":"Nasal administration; Antigen; Immunogenicity; Microbiology; Adjuvant; Immunology; Immunization; Antibody; Vaccination; Cholera toxin; Immunoglobulin A; Biology; Virology; Immunoglobulin G","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002564017,0.0005532554,0.0003793527,0.0002359119,0.00005714267,0.0002156912,0.0001818748,0.0003755666,0.000972758],"category_scores_gemma":[0.0001712741,0.0001222688,0.0002439263,0.000110448,0.0001756434,0.0002017238,0.0002330894,0.0008903489,0.0002471751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001750959,"about_ca_system_score_gemma":0.0001375823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001238425,"about_ca_topic_score_gemma":0.0002627692,"domain_scores_codex":[0.9998139,0.00003546654,0.00001172041,0.00002913708,0.00004436333,0.00006552874],"domain_scores_gemma":[0.9998637,0.00003337549,0.00003946555,0.00001324498,0.00001779941,0.00003244745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002091579,0.0001631238,0.0001611463,0.00006474312,0.000006837608,0.00001443415,0.000009017838,0.00007147183,0.9971569,0.00001885628,0.0000294737,0.002094834],"study_design_scores_gemma":[0.0001842301,0.01206527,0.008717631,0.00003377764,0.00009061877,0.0002360301,0.00003098907,0.001303609,0.9753886,0.00004868946,0.001895673,0.00000503995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965071,0.0009982272,0.001609406,0.00005444335,0.00002636163,0.00005014758,0.00007889434,0.00006783705,0.0006075535],"genre_scores_gemma":[0.9957229,0.0008286654,0.002295094,0.00005982806,0.00002664027,0.0000377715,0.0002430704,0.00001208907,0.0007740775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000972758,"threshold_uncertainty_score":0.003254175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01464205355713585,"score_gpt":0.2620174229085237,"score_spread":0.2473753693513878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}