{"id":"W4393408929","doi":"10.31234/osf.io/ju4ya","title":"Methods for Neuroscience Drug Development: Guidance on Standardization of the Process for Defining Clinical Outcome Strategies in Clinical Trials","year":2024,"lang":"en","type":"preprint","venue":"","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sante Montreal","funders":"European College of Neuropsychopharmacology","keywords":"Standardization; Outcome (game theory); Drug development; Clinical trial; Process (computing); Neuroscience; Psychology; Process management; Medicine; Management science; Computer science; Drug; Psychiatry; Engineering; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.4710654,0.005194828,0.005982629,0.01143785,0.003151337,0.0152371,0.009900605,0.02128876,0.02061227],"category_scores_gemma":[0.5498554,0.005593061,0.01244206,0.009959896,0.008820676,0.009563206,0.00918946,0.02908442,0.02875438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00896438,"about_ca_system_score_gemma":0.04758824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004256571,"about_ca_topic_score_gemma":0.006308416,"domain_scores_codex":[0.4337504,0.4545235,0.05599291,0.006413899,0.04662846,0.002690824],"domain_scores_gemma":[0.3714309,0.4772847,0.03000986,0.04804568,0.06785165,0.005377121],"domain_codex":"methods","domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0009799972,0.0004675553,0.0008552042,0.01603435,0.0008198561,0.0004548197,0.003754368,0.003501508,0.001058363,0.1924913,0.2990746,0.480508],"study_design_scores_gemma":[0.001848713,0.0007503317,0.002431289,0.03124943,0.000769902,0.00091652,0.0005515181,0.005851821,0.003025631,0.2402579,0.7118842,0.0004626602],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.0006891815,0.01685223,0.8729795,0.03880539,0.003926243,0.03331368,0.003566327,0.003103201,0.02676424],"genre_scores_gemma":[0.00301082,0.005324384,0.9530019,0.005652485,0.0005804667,0.02789561,0.0009266246,0.000535106,0.003072763],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.4710654,"threshold_uncertainty_score":0.6522706,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.8428571500018572,"score_gpt":0.6929898175079824,"score_spread":0.1498673324938748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}