{"id":"W4393411060","doi":"10.1128/spectrum.04041-23","title":"Approaches for identifying and measuring heteroresistance in azole-susceptible <i>Candida</i> isolates","year":2024,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fondation pour la Recherche Médicale; Agence Nationale de la Recherche; Canadian Institute for Advanced Research","keywords":"Candida albicans; Biology; Population; Azole; Computational biology; Profiling (computer programming); Context (archaeology); Corpus albicans; Microbiology; Antifungal; Medicine; Computer science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003783477,0.0001868438,0.0003644329,0.0001598725,0.00008556093,0.00005060691,0.00007548834,0.0001486396,0.0000316806],"category_scores_gemma":[0.0000372509,0.0001612344,0.0001098284,0.0001780844,0.0001850816,0.0000951357,0.00004485741,0.000252948,0.0000186383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001153799,"about_ca_system_score_gemma":0.00006175868,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003163841,"about_ca_topic_score_gemma":0.001061982,"domain_scores_codex":[0.9986386,0.0000350347,0.0002885459,0.0005656917,0.00003532143,0.0004367932],"domain_scores_gemma":[0.9995814,0.0001042022,0.00003130805,0.0002063609,0.00001468475,0.00006207207],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005294158,0.00007645006,0.08925515,0.001278787,0.00009964067,0.00005026155,0.0005351253,0.000002182975,0.9041555,0.001760468,0.0007911036,0.001465936],"study_design_scores_gemma":[0.00902709,0.002453051,0.2838934,0.004945663,0.0006202443,0.001232573,0.003375015,0.003618921,0.6088316,0.02531116,0.05432242,0.002368854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802311,0.01517275,0.001723692,0.001429111,0.0002214976,0.000500749,0.00003376297,0.0001029393,0.0005843944],"genre_scores_gemma":[0.9977172,0.0002151417,0.000768217,0.0001637954,0.0001055371,0.00003581613,0.00003739494,0.00002739487,0.0009294956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2953238,"threshold_uncertainty_score":0.6574948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05817012966664773,"score_gpt":0.2827556319272726,"score_spread":0.2245855022606249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}