{"id":"W4393411060","doi":"10.1128/spectrum.04041-23","title":"Approaches for identifying and measuring heteroresistance in azole-susceptible <i>Candida</i> isolates","year":2024,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fondation pour la Recherche Médicale; Agence Nationale de la Recherche; Canadian Institute for Advanced Research","keywords":"Candida albicans; Biology; Population; Azole; Computational biology; Profiling (computer programming); Context (archaeology); Corpus albicans; Microbiology; Antifungal; Medicine; Computer science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00153841,0.0009537929,0.0009293225,0.00232657,0.0004929364,0.001588602,0.001122148,0.0008241931,0.000894565],"category_scores_gemma":[0.00145553,0.000457938,0.0007463728,0.001353603,0.0005167651,0.0004947664,0.001144081,0.001481222,0.0009038128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005487002,"about_ca_system_score_gemma":0.0007244104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001740929,"about_ca_topic_score_gemma":0.003214204,"domain_scores_codex":[0.9978036,0.0004865148,0.0002687469,0.0004542006,0.0008529722,0.0001340041],"domain_scores_gemma":[0.9983795,0.0002705271,0.0004754265,0.0002366534,0.0005421893,0.00009565229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005422089,0.0001136621,0.005250668,0.0003245801,0.00005221254,0.00004799363,0.00009639177,0.0004570063,0.9733392,0.0002573054,0.0003718781,0.01963495],"study_design_scores_gemma":[0.000009614571,0.000345409,0.01887809,0.00008443376,0.000110162,0.0004637265,0.0002351212,0.006423989,0.9678423,0.0003872318,0.005133029,0.00008691631],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.4588284,0.008507107,0.5136879,0.0009219213,0.0002356352,0.001500885,0.00678209,0.00363141,0.005904625],"genre_scores_gemma":[0.5230918,0.005375839,0.4622762,0.0004910576,0.00006306658,0.001493005,0.003920183,0.0002791279,0.003009767],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.00232657,"threshold_uncertainty_score":0.008135974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05817012966664773,"score_gpt":0.2827556319272726,"score_spread":0.2245855022606249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}