{"id":"W4393763332","doi":"10.5281/zenodo.5517654","title":"Spliced isoforms of the cardiac Nav1.5 channel modify channel activation by distinct structural mechanisms: Molecular dynamics coordinate and trajectory files","year":2022,"lang":"en","type":"dataset","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Gene isoform; Trajectory; Channel (broadcasting); Dynamics (music); Focus (optics); Reaction coordinate; Computer science; Computational biology; Biological system; Physics; Chemistry; Biology; Genetics; Gene; Computer network; Computational chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005327224,0.002077327,0.001166161,0.001093286,0.0006408063,0.001301964,0.002369302,0.002614205,0.04564648],"category_scores_gemma":[0.002839524,0.0006126103,0.001862202,0.002094168,0.0003159326,0.0008217272,0.0009457091,0.001447254,0.03262579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001279145,"about_ca_system_score_gemma":0.001788784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01788047,"about_ca_topic_score_gemma":0.03176535,"domain_scores_codex":[0.9995847,0.00005982207,0.00004128882,0.0001290382,0.0001236501,0.0000614505],"domain_scores_gemma":[0.999045,0.0004301912,0.00009912116,0.0001882873,0.0001644396,0.00007293806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003064319,0.00006469718,0.002082978,0.001638314,0.0001477466,0.0001153121,0.000027461,0.007532479,0.0006339209,0.001443235,0.9812188,0.004788612],"study_design_scores_gemma":[0.002951089,0.0001253654,0.01486292,0.0006847688,0.0002956908,0.0004118006,0.00009122535,0.02452329,0.004538806,0.009823745,0.9415457,0.0001455099],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0007966976,0.0001448898,0.0002373793,0.00008504241,0.00002808207,0.00001236116,0.9971771,0.0008690181,0.0006493168],"genre_scores_gemma":[0.002964214,0.000144111,0.0006733726,0.00005578673,0.000009664861,0.00009150214,0.9953421,0.00012928,0.0005900651],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.04564648,"threshold_uncertainty_score":0.1527027,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009629418879348834,"score_gpt":0.2228279984976317,"score_spread":0.2131985796182828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}