{"id":"W4393859731","doi":"10.3390/curroncol31040143","title":"A Review of Practice-Changing Therapies in Oncology in the Era of Personalized Medicine","year":2024,"lang":"en","type":"review","venue":"Current Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University; St Mary's Hospital Centre; Jewish General Hospital","funders":"","keywords":"Medicine; Chimeric antigen receptor; Personalized medicine; Precision medicine; Microbiome; Cancer; Bioinformatics; Cancer treatment; Computational biology; Immunotherapy; Internal medicine; Biology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001459908,0.0007393816,0.001147309,0.00260994,0.0004102603,0.001564324,0.0009843544,0.001843454,0.006914586],"category_scores_gemma":[0.003273647,0.0002990376,0.0007568951,0.003020447,0.0006093718,0.002005791,0.0008959383,0.002564708,0.002363945],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001639207,"about_ca_system_score_gemma":0.003118047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001541793,"about_ca_topic_score_gemma":0.003761268,"domain_scores_codex":[0.9993673,0.0001919124,0.00009967591,0.00008266245,0.0002085088,0.00004992851],"domain_scores_gemma":[0.9980558,0.001243705,0.0001753512,0.00003239965,0.0003951801,0.00009759105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00005739213,0.00004142048,0.000103293,0.04168115,0.00009161857,0.0001707902,0.0001690349,0.0003628559,0.0004836542,0.00876867,0.1184504,0.8296198],"study_design_scores_gemma":[0.000009104986,0.0000375755,0.0002322783,0.01322199,0.00005751714,0.0004533335,0.00006773046,0.00004479884,0.0000562873,0.001692214,0.9841165,0.00001064781],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003870115,0.9966317,0.000113177,0.001552681,0.0007578314,0.000006204805,0.00001780086,0.000006233142,0.0008757582],"genre_scores_gemma":[0.0002951543,0.9975097,0.000189,0.001055758,0.0005453174,0.000008552513,0.00002130106,0.000002257538,0.0003729454],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006914586,"threshold_uncertainty_score":0.02313161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3230535930040258,"score_gpt":0.5797166237464436,"score_spread":0.2566630307424179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}