{"id":"W4393859830","doi":"10.1002/adhm.202400235","title":"Antibody‐Conjugated Nanogel with Two Immune Checkpoint Inhibitors for Enhanced Cancer Immunotherapy","year":2024,"lang":"en","type":"article","venue":"Advanced Healthcare Materials","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nexen (Canada)","funders":"National Research Foundation of Korea","keywords":"Immunotherapy; Monoclonal antibody; Immune system; Antibody; Cancer research; Cancer; Cancer immunotherapy; Antigen; Medicine; Cancer cell; Breast cancer; Immunology; Cytotoxic T cell; Metastatic breast cancer; In vitro; Biology; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001063297,0.0002892229,0.0001699325,0.0001650997,0.00005932553,0.0001594903,0.0001375949,0.0002774709,0.0008174603],"category_scores_gemma":[0.00006613301,0.0001064366,0.0002164735,0.00005817853,0.000126328,0.0002173686,0.0001523503,0.0003312619,0.0002088421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001925327,"about_ca_system_score_gemma":0.0001392622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001339112,"about_ca_topic_score_gemma":0.000294457,"domain_scores_codex":[0.9999442,0.000006361867,0.000003876198,0.0000147677,0.00001855943,0.0000120874],"domain_scores_gemma":[0.9999709,0.000006241198,0.000007916084,0.000002065433,0.000005243755,0.000007665912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000267293,0.00002073356,0.00001677,0.00003593603,0.000003286877,0.000009624933,0.000004813455,0.00009594593,0.9981607,0.0001137583,0.00003342542,0.001478244],"study_design_scores_gemma":[0.00001513722,0.0003092351,0.0002331297,0.000005794139,0.00001385467,0.00006515808,0.000004721603,0.0008434134,0.9953367,0.00002993286,0.003139253,0.000003605525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9514452,0.006103265,0.03507667,0.0002487833,0.0003296195,0.0001167898,0.0001437664,0.0002621668,0.006273755],"genre_scores_gemma":[0.9747036,0.002022455,0.0184512,0.0003044207,0.00003887221,0.0001099526,0.000149031,0.00004290968,0.004177596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008174603,"threshold_uncertainty_score":0.002734661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01587229500458322,"score_gpt":0.3596063736358575,"score_spread":0.3437340786312743,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}