{"id":"W4393864250","doi":"10.3892/ol.2024.14377","title":"Oncolytic virotherapy stimulates anti‑tumor immune response and demonstrates activity in advanced sarcoma: Report of two cases","year":2024,"lang":"en","type":"article","venue":"Oncology Letters","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Biotech (Canada)","funders":"","keywords":"Oncolytic virus; Medicine; Sarcoma; Cancer; Soft tissue sarcoma; Clinical trial; Oncology; Internal medicine; Immune system; Immunology; Cancer research; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009266068,0.0001858791,0.0003284248,0.0001780455,0.00004680323,0.00001885301,0.0001456029,0.0001100893,0.00002076731],"category_scores_gemma":[0.0001386244,0.0001779302,0.00008067839,0.0001966093,0.0003798739,0.00001132322,0.00007440239,0.0002234423,0.000003349608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008729491,"about_ca_system_score_gemma":0.0003501888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008157695,"about_ca_topic_score_gemma":0.0001999055,"domain_scores_codex":[0.9984275,0.0003465404,0.0003104681,0.0004708281,0.0001227868,0.0003219537],"domain_scores_gemma":[0.999118,0.0003468264,0.00009036867,0.0003488833,0.00003218266,0.00006371924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008176091,0.0001344683,0.004708469,0.00003350175,0.00008986131,0.003038637,0.00004762211,0.0002796753,0.9733412,0.00000339364,0.0001091417,0.010038],"study_design_scores_gemma":[0.001878208,0.004141557,0.01780452,0.00005502949,0.0000170966,0.001108543,0.00003921967,0.0002903191,0.9722139,0.00002601623,0.002208731,0.000216916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937506,0.002912888,0.000066794,0.002724956,0.0001107394,0.0003501875,0.00001561036,0.00001984896,0.00004842314],"genre_scores_gemma":[0.9987017,0.0002558652,0.0004311769,0.000375482,0.00005600547,0.0000470681,0.00001400619,0.00003400765,0.00008471463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01309605,"threshold_uncertainty_score":0.7255781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01673433169337609,"score_gpt":0.353120828991763,"score_spread":0.3363864972983869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}