{"id":"W4393950385","doi":"10.1016/j.stem.2024.03.009","title":"Genetic haute couture to block HIV-1 at front doors","year":2024,"lang":"en","type":"article","venue":"Cell stem cell","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Doors; Biology; Block (permutation group theory); Human immunodeficiency virus (HIV); Front (military); Virology; Engineering; Mechanical engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000567465,0.0005480562,0.0004719784,0.0004432702,0.0006342959,0.001561522,0.0007415328,0.0009400822,0.01356313],"category_scores_gemma":[0.0008089685,0.0003561214,0.0004932487,0.000204426,0.000908028,0.0008610844,0.0007022775,0.003339134,0.00259729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006962111,"about_ca_system_score_gemma":0.0007662906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001005297,"about_ca_topic_score_gemma":0.001649355,"domain_scores_codex":[0.9995298,0.00008523151,0.00002411859,0.00008165216,0.0001736565,0.0001056384],"domain_scores_gemma":[0.9996322,0.0001085542,0.0000603969,0.00006922935,0.0000483461,0.0000811261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004060864,0.0002717608,0.0003465775,0.0002074494,0.00006004715,0.0002368613,0.0001343219,0.001958932,0.9114854,0.03597195,0.006176589,0.04274409],"study_design_scores_gemma":[0.0001484261,0.001144554,0.0007104914,0.00007669225,0.00007745328,0.0007930906,0.0001143817,0.00314391,0.8248841,0.00932222,0.1595311,0.00005355437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6247495,0.03211267,0.1713132,0.02458522,0.01155438,0.0007425415,0.002412162,0.00970053,0.1228298],"genre_scores_gemma":[0.9085172,0.006625064,0.03602366,0.003818477,0.0004764277,0.0002087262,0.0005570612,0.0005377133,0.04323571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01356313,"threshold_uncertainty_score":0.0453732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00788168754918096,"score_gpt":0.2166617427250685,"score_spread":0.2087800551758875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}