{"id":"W4393972654","doi":"10.1089/dna.2024.0057","title":"Anti-Inflammatory Effects of Glucagon-Like Peptide-1 Receptor Agonists via the Neuroimmune Axis","year":2024,"lang":"en","type":"article","venue":"DNA and Cell Biology","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"","keywords":"Inflammation; Biology; Receptor; Glucagon-like peptide-1; Sepsis; Toll-like receptor; Glucagon-like peptide 1 receptor; Neuroscience; Immunology; Pharmacology; Agonist; Type 2 diabetes; Endocrinology; Diabetes mellitus; Innate immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000392847,0.0004474609,0.000650094,0.001100579,0.0001783764,0.0007816114,0.0003543566,0.0005057279,0.001157508],"category_scores_gemma":[0.0003369968,0.0000920994,0.0003119311,0.000603498,0.0003535849,0.0008280646,0.0003398879,0.0006873623,0.000428991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003498924,"about_ca_system_score_gemma":0.0004622391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002354858,"about_ca_topic_score_gemma":0.0004409369,"domain_scores_codex":[0.9998741,0.00002474437,0.00002227829,0.00001950564,0.00003929493,0.00002001743],"domain_scores_gemma":[0.9998073,0.00007475665,0.00004788205,0.000004370774,0.0000497069,0.00001598517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004078626,0.000146123,0.001247688,0.01324642,0.0001147333,0.001762554,0.0002239712,0.0003340212,0.09074139,0.006148789,0.005166612,0.8804598],"study_design_scores_gemma":[0.00006810692,0.002245061,0.01761101,0.005624408,0.0007019587,0.01302067,0.001091565,0.0006664649,0.08401305,0.0128738,0.8619645,0.0001193466],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.006079319,0.9887639,0.001187168,0.001201414,0.0003715894,0.00000954463,0.00003432924,0.00002105246,0.002331726],"genre_scores_gemma":[0.01467545,0.9823139,0.001016958,0.0005344071,0.0006899145,0.00001210235,0.00003879219,0.000003869857,0.0007145878],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001157508,"threshold_uncertainty_score":0.003872275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008814733892888072,"score_gpt":0.2236338136165376,"score_spread":0.2148190797236495,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}