{"id":"W4393988317","doi":"10.1158/1538-7445.am2024-ct054","title":"Abstract CT054: Amivantamab in wild-type advanced non-small cell lung cancer after disease progression on checkpoint inhibition and chemotherapy: Results from the phase 1b CHRYSALIS study","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Chemotherapy; Medicine; Cancer; Oncology; Lung cancer; Cancer research; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007913501,0.0005677555,0.0006720396,0.0002079093,0.0001932648,0.0006602404,0.0003560282,0.0005478074,0.001906298],"category_scores_gemma":[0.0004003017,0.0001275667,0.000875864,0.0002900685,0.000270039,0.0003579084,0.0002213814,0.0009583946,0.0004970564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006361676,"about_ca_system_score_gemma":0.0005945992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001004506,"about_ca_topic_score_gemma":0.002492033,"domain_scores_codex":[0.9997421,0.0001038918,0.00002122006,0.00004393169,0.00004820891,0.00004064885],"domain_scores_gemma":[0.9996983,0.00004082294,0.00006919735,0.00002684855,0.00004181167,0.0001230002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5683136,0.02234011,0.07799974,0.001741174,0.005594077,0.0004521893,0.0002805807,0.002665771,0.1036088,0.0003261946,0.009703365,0.2069743],"study_design_scores_gemma":[0.2553957,0.4327443,0.2750696,0.0001654611,0.004706268,0.001336866,0.0002206573,0.002647752,0.01726923,0.000379027,0.009991782,0.00007354911],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941917,0.002732097,0.0001158041,0.0002016613,0.00002761068,0.0002288895,0.001285525,0.0000225239,0.001194228],"genre_scores_gemma":[0.9946058,0.001146011,0.0001654411,0.0002296269,0.00003754288,0.0001203854,0.002705859,0.000007596027,0.0009815956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001906298,"threshold_uncertainty_score":0.00637722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03345896056272359,"score_gpt":0.4453993473951861,"score_spread":0.4119403868324625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}