{"id":"W4393989833","doi":"10.1158/1538-7445.am2024-ct280","title":"Abstract CT280: FURVENT, Phase 3 trial testing furmonertinib vs chemotherapy as first-line treatment for advanced NSCLC with EGFR exon 20 insertions (FURMO-004)","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; Exon; Oncology; Chemotherapy; Internal medicine; Phases of clinical research; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001284415,0.001382544,0.001185318,0.0003760424,0.0004364603,0.001163835,0.0008867998,0.001776195,0.01541303],"category_scores_gemma":[0.001086783,0.0004158462,0.001442607,0.0002912201,0.0006742339,0.0009039557,0.0003800861,0.003588788,0.002796405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001034243,"about_ca_system_score_gemma":0.001374066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001460456,"about_ca_topic_score_gemma":0.004146509,"domain_scores_codex":[0.999757,0.0001190382,0.00001084751,0.00003641067,0.00002802255,0.00004867103],"domain_scores_gemma":[0.9994923,0.0001182536,0.0001000068,0.00003024583,0.00003554512,0.0002237144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8481933,0.02030243,0.002669997,0.001724271,0.001391987,0.0002888238,0.0002173738,0.002378579,0.02691041,0.000899771,0.02868757,0.06633545],"study_design_scores_gemma":[0.7735607,0.2100431,0.005705532,0.0001074036,0.000355064,0.000274351,0.00004360479,0.001748009,0.001722305,0.0004263517,0.005983833,0.00002989141],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9503364,0.006059624,0.0008752825,0.00328709,0.0006402448,0.006303648,0.01442059,0.0006886229,0.01738859],"genre_scores_gemma":[0.9425964,0.00359423,0.002270334,0.004595361,0.000573842,0.005732264,0.01832225,0.0001263653,0.02218885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01541303,"threshold_uncertainty_score":0.05156165,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1740233163490172,"score_gpt":0.5215673596128443,"score_spread":0.347544043263827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}