{"id":"W4394012424","doi":"10.1101/2024.04.05.588257","title":"<i>In vitro</i> host transcriptomics during <i>Cryptococcus neoformans</i> , <i>Cryptococcus gattii</i> , and <i>Candida albicans</i> infection of South African volunteers","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"University of Cape Town; National Institute for Health and Care Research; Government of the United Kingdom; Department of Health and Social Care; Wellcome Trust","keywords":"Cryptococcus neoformans; Candida albicans; Microbiology; Cryptococcus; Cryptococcus gattii; Biology; Host (biology); Cryptococcosis; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002061676,0.0001981394,0.0002263258,0.0001783851,0.0002615983,0.0004335185,0.00008170417,0.0002797639,0.002814427],"category_scores_gemma":[0.0002153078,0.00009771662,0.0001887213,0.0002151264,0.000264944,0.00008708786,0.0001883316,0.0003484346,0.0005651073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001495816,"about_ca_system_score_gemma":0.0001644595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007423328,"about_ca_topic_score_gemma":0.0009755944,"domain_scores_codex":[0.9998548,0.0000293994,0.00000697638,0.00004498367,0.00002554993,0.00003828839],"domain_scores_gemma":[0.9999207,0.00002888862,0.00001314508,0.00000868734,0.00001368835,0.00001485276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007135986,0.0000406591,0.003871037,0.00007113662,0.000008256269,0.00008439195,0.0001442128,0.00006238977,0.9935272,0.00002483119,0.0001600545,0.001292159],"study_design_scores_gemma":[0.00007547053,0.002446595,0.3665621,0.00006927163,0.00008502148,0.001205269,0.001976443,0.001457329,0.6194223,0.0002572468,0.006412729,0.00003026767],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953057,0.0005716428,0.0006710856,0.0001215672,0.0000370868,0.00004998119,0.002397276,0.00001810473,0.0008275085],"genre_scores_gemma":[0.9912389,0.0005302028,0.00147839,0.0002563025,0.00003535796,0.0001348602,0.003538924,0.00001744419,0.002769669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002814427,"threshold_uncertainty_score":0.009415269,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008285173903800321,"score_gpt":0.2165257566691788,"score_spread":0.2082405827653784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}