{"id":"W4394013257","doi":"10.1001/jama.2024.3841","title":"Prostate Cancer Screening With PSA, Kallikrein Panel, and MRI","year":2024,"lang":"en","type":"letter","venue":"JAMA","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"National Cancer Institute","keywords":"Medicine; Prostate cancer; Prostate; Cancer; Prostate-specific antigen; Kallikrein; Oncology; Randomized controlled trial; Internal medicine; Urology; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006849643,0.0003935006,0.0005384195,0.0001245156,0.0000564436,0.000160071,0.00006184524,0.0003469304,0.0001816094],"category_scores_gemma":[0.000007385225,0.0002580943,0.00008154323,0.0001472331,0.00009803828,0.00007824498,0.00006283399,0.001201213,0.00004794554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001880091,"about_ca_system_score_gemma":0.0002119977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006417845,"about_ca_topic_score_gemma":0.00006790026,"domain_scores_codex":[0.998309,0.00002262852,0.0002203224,0.0006540343,0.0003728312,0.0004212262],"domain_scores_gemma":[0.9992996,0.00005833971,0.00009899119,0.0003216137,0.0001018254,0.0001196184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001506493,0.00002296133,0.006582272,0.001283245,0.0007502518,0.006380822,0.0003066987,0.000003028243,0.000006874496,0.000008471631,0.9337574,0.05074728],"study_design_scores_gemma":[0.002160158,0.0005835202,0.005004041,0.004351804,0.0009699067,0.0001715099,0.00003138418,0.00004231878,0.0002511441,0.00004708897,0.9860785,0.0003086407],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.006910243,0.02623147,0.00001252964,0.9629669,0.0002638575,0.001070184,0.0004300167,0.0001264059,0.001988465],"genre_scores_gemma":[0.00529735,0.01628723,0.001352874,0.9335625,0.006212997,0.00153316,0.001005946,0.0002556157,0.03449231],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.05232103,"threshold_uncertainty_score":0.9999871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0261314852566597,"score_gpt":0.2744134960296447,"score_spread":0.248282010772985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}