{"id":"W4394082753","doi":"10.6084/m9.figshare.20418213","title":"Additional file 3 of Target residence of Cas9-sgRNA influences DNA double-strand break repair pathway choices in CRISPR/Cas9 genome editing","year":2022,"lang":"en","type":"dataset","venue":"Open MIND","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"CRISPR; Genome editing; Subgenomic mRNA; Cas9; Genetics; Biology; DNA; Computational biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001564525,0.001402967,0.001710706,0.002406246,0.0007196842,0.002208678,0.002066713,0.001696133,0.4979877],"category_scores_gemma":[0.01581557,0.0005880561,0.001366873,0.004242467,0.0003438249,0.001397866,0.001437239,0.001302105,0.09741502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001156606,"about_ca_system_score_gemma":0.00213794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01062218,"about_ca_topic_score_gemma":0.02066687,"domain_scores_codex":[0.9989308,0.0001744186,0.0001794486,0.0003685168,0.0002053296,0.000141557],"domain_scores_gemma":[0.9892851,0.007845848,0.000708914,0.0007358253,0.001080312,0.0003441744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000314831,0.00005210993,0.003476997,0.005123995,0.0001314851,0.00005058091,0.00004418419,0.0006354874,0.0001947504,0.0005827124,0.9849464,0.004446513],"study_design_scores_gemma":[0.003381071,0.0001326941,0.01934508,0.002882405,0.0003483115,0.0002122959,0.0002186513,0.001178331,0.001031112,0.004974523,0.9662021,0.00009348072],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.00004640405,0.00001240623,0.00003117323,0.00001964824,0.000003604075,0.000007194362,0.9996843,0.00006017451,0.0001350747],"genre_scores_gemma":[0.001307134,0.00005797268,0.0005335539,0.0001086662,0.000009384233,0.0002839524,0.9965132,0.0001515762,0.001034648],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.4979877,"threshold_uncertainty_score":0.7160597,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01595037167352723,"score_gpt":0.3055467474937591,"score_spread":0.2895963758202318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}