{"id":"W4394174479","doi":"10.6084/m9.figshare.19925659","title":"Fluorofenidone inhibits epithelial-mesenchymal transition in human lens epithelial cell line FHL 124: a promising therapeutic strategy against posterior capsular opacification","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"CTGF; Western blot; Molecular biology; Lactate dehydrogenase; Epithelial–mesenchymal transition; Viability assay; MTT assay; Cell culture; Cell growth; Growth factor; Mesenchymal stem cell; Immunocytochemistry; Chemistry; Transforming growth factor; Cell; Biology; Cell biology; Downregulation and upregulation; Biochemistry; Endocrinology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002584777,0.0005699577,0.0004812153,0.0003410827,0.0002661348,0.0001260048,0.0006395541,0.0006255978,0.05941538],"category_scores_gemma":[0.0002044803,0.000639501,0.0001916959,0.0003217491,0.00003582316,0.0000236232,0.0003366391,0.0009619957,0.0001800968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002022992,"about_ca_system_score_gemma":0.0004558319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001562424,"about_ca_topic_score_gemma":0.0003207918,"domain_scores_codex":[0.9965445,0.0005385613,0.0005960521,0.001116288,0.0005357185,0.0006688848],"domain_scores_gemma":[0.9983965,0.00004144158,0.0003028466,0.0008925948,0.0002283832,0.0001382616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000151729,0.0002304329,0.000001267755,0.0005554312,0.00004732894,0.00007970755,0.0000953795,0.00007864815,0.8115785,1.66764e-7,0.185966,0.001215469],"study_design_scores_gemma":[0.001635647,0.001222915,0.0002387857,0.0005975619,0.0000424356,0.00003054955,0.0001440612,0.00003462596,0.4069916,0.000007646257,0.588152,0.0009021275],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.08139409,0.001215469,0.000001267513,0.00006810136,0.0000758534,0.001467356,0.9156953,0.00002470228,0.00005789974],"genre_scores_gemma":[0.1489596,0.0000890619,0.000004632565,0.0001078179,0.000404151,0.0006221575,0.849618,0.00008260642,0.0001119486],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.4045868,"threshold_uncertainty_score":0.9996057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04660997310031757,"score_gpt":0.3043350948314485,"score_spread":0.2577251217311309,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}