{"id":"W4394202450","doi":"10.6084/m9.figshare.17124847","title":"Additional file 1 of A functionally impaired missense variant identified in French Canadian families implicates FANCI as a candidate ovarian cancer-predisposing gene","year":2021,"lang":"en","type":"dataset","venue":"Open MIND","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Missense mutation; Ovarian cancer; Candidate gene; Gene; Biology; Genetics; Cancer; Bioinformatics; Medicine; Mutation","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008494767,0.001105536,0.00136038,0.001958217,0.0007636451,0.001521403,0.001974775,0.001451649,0.3621878],"category_scores_gemma":[0.01145028,0.0004479098,0.001054373,0.003379096,0.0003074173,0.0008633017,0.00109581,0.0009979878,0.04905544],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001709921,"about_ca_system_score_gemma":0.002637201,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.04008993,"about_ca_topic_score_gemma":0.08155444,"domain_scores_codex":[0.9995192,0.00006460498,0.00007465803,0.000166458,0.00008096667,0.00009397935],"domain_scores_gemma":[0.9950388,0.003009312,0.0004843443,0.0004417426,0.0007308047,0.0002950703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.0003291946,0.00004479734,0.006164819,0.00340894,0.0001323937,0.0001175961,0.0000382482,0.0004892987,0.0001693521,0.0007708555,0.9830809,0.005253608],"study_design_scores_gemma":[0.003072293,0.00009593029,0.05132759,0.002996438,0.0004504179,0.000780567,0.0001705717,0.0008241793,0.0006873233,0.004913779,0.9345989,0.00008199658],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0001120817,0.00003424329,0.00003324349,0.0000296195,0.000004263734,0.000009178897,0.9994422,0.00003354697,0.000301639],"genre_scores_gemma":[0.00241935,0.0001083173,0.0003851076,0.0001459174,0.00001233555,0.0001719631,0.9954361,0.0000714033,0.001249572],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.9599101,"threshold_uncertainty_score":0.9097617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01523102483213541,"score_gpt":0.2813029948360294,"score_spread":0.266071970003894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}